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NeoBiotechnologies
TLE1 (Synovial Sarcoma Marker) Recombinant Mouse Monoclonal Antibody (rTLE1/13032)
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FIGURE: 1 / 2
TLE1 (Synovial Sarcoma Marker) Antibody (7088-MSM8-P1ABX) in IHC (P)
Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human endometrium stained with TLE1 Recombinant Mouse Monoclonal Antibody (rTLE1/13032). Inset: PBS instead of primary antibody; secondary only negative control.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
7088-MSM8-P1ABX
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
rTLE1/13032
Immunogen
Recombinant full-length human TLE1 protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: enhancer of split groucho-like protein 1; RP11-203D19.1; TLE 1; transducin like enhancer of split 1; transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila); unnamed protein product
Gene Aliases: ESG; ESG1; GRG1; TLE-1
UniProt ID: (Human) Q04724
Entrez Gene ID: (Human) 7088
regulation of transcription, DNA-templated
signal transduction
organ morphogenesis
positive regulation of gene expression
negative regulation of Wnt signaling pathway
negative regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of transcription, DNA-templated
negative regulation of canonical Wnt signaling pathway
negative regulation of anoikis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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