1-Fluoro-4-iodobenzene, 99%
1-Fluoro-4-iodobenzene, 99%
1-Fluoro-4-iodobenzene, 99%
Thermo Scientific Chemicals

1-Fluoro-4-iodobenzene, 99%

CAS: 352-34-1 | C6H4FI | 222.00 g/mol
Quantity:
10 g
50 g
250 g
Catalog number A12008.30
also known as A12008-30
Price (JPY)
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Quantity:
250 g
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Chemical Identifiers
CAS352-34-1
SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)Clear colorless to yellow
FormLiquid
Assay (GC)≥98.5%
Identification (FTIR)Conforms
Refractive Index1.5815-1.5845 @ 20?C
4-Fluoroiodobenzene was used in the preparation of fluorotriphenylene derivatives. 4-[F] Fluoroiodobenzene is a versatile building block in 18F radiochemistry and is used in various transition metal-mediated C-C and C-N cross-coupling reactions.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Fluoroiodobenzene was used in the preparation of fluorotriphenylene derivatives. 4-[F] Fluoroiodobenzene is a versatile building block in 18F radiochemistry and is used in various transition metal-mediated C-C and C-N cross-coupling reactions.

Solubility
Insoluble in water.

Notes
Light Sensitive. Store in cool dry place. Keep container tightly sealed.
RUO – Research Use Only

General References:

  1. Jerry M. Meyersa.; Andrew J. Gellman. Effect of substituents on the phenyl coupling reaction on Cu(111).Surface Science. 1995, 337 (1-2), 40-50.
  2. Hülya Akgün.; Tomas Hudlicky. Total syntheses of ert-conduramine A and ent-7-deoxypancratistatin. Tetrahedron Lett. 1999, 40 (16),3081-3084.
  3. Regioselective metallation can be accomplished with LDA ortho to the fluoro substituent: Tetrahedron Lett., 33, 7499 (1992). Subsequent carboxylation and F - displacement with an amine has been used to synthesize 5-iodoanthranilic acid derivatives: J. Med. Chem., 40, 717 (1997).