Search
Element Search
Structure Search
Thermo Scientific Chemicals
2-Hydroxyisobutyric acid, 99% (dry wt.), water <2%
CAS: 594-61-6 | C4H8O3 | 104.11 g/mol
Change view
Catalog number A13146.14
also known as A13146-14
Price (JPY)
-
Quantity:
25 g
Chemical Identifiers
CAS594-61-6
IUPAC Name2-hydroxy-2-methylpropanoic acid
Molecular FormulaC4H8O3
InChI KeyBWLBGMIXKSTLSX-UHFFFAOYSA-N
SMILESCC(C)(O)C(O)=O
View more
Specifications
Specification Sheet
Specification SheetAppearance (Color)White to pale cream
Assay (Aqueous acid-base Titration)≥98.5 to ≤101.5% (dry wt. basis)
Assay (Silylated GC)≥98.5%
Water Content (Karl Fischer Titration)≤2.0%
Melting Point (clear melt)75-81?C
View more
2-Hydroxyisobutyric acid is used as an electrolyte in the separation of the metal ions by on-line cyclic voltammetry. It is also used as a building block for the synthesis of polymers. Its conjugate base, 2-hydroxybutyrate is utilized to catabolize L-threonine as well as synthesize glutathione. Further, it is used as an indicator for the early detection insulin resistance in non-diabetic subjects.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Hydroxyisobutyric acid is used as an electrolyte in the separation of the metal ions by on-line cyclic voltammetry. It is also used as a building block for the synthesis of polymers. Its conjugate base, 2-hydroxybutyrate is utilized to catabolize L-threonine as well as synthesize glutathione. Further, it is used as an indicator for the early detection insulin resistance in non-diabetic subjects.
Solubility
Soluble in water, ether, alcohol, methanol and hot benzene.
Notes
Incompatible with oxidizing agents, bases and reducing agents.
2-Hydroxyisobutyric acid is used as an electrolyte in the separation of the metal ions by on-line cyclic voltammetry. It is also used as a building block for the synthesis of polymers. Its conjugate base, 2-hydroxybutyrate is utilized to catabolize L-threonine as well as synthesize glutathione. Further, it is used as an indicator for the early detection insulin resistance in non-diabetic subjects.
Solubility
Soluble in water, ether, alcohol, methanol and hot benzene.
Notes
Incompatible with oxidizing agents, bases and reducing agents.
RUO – Research Use Only
General References:
- Przybylski, D.; Rohwerder, T.; Dilßner, C.; Maskow, T.; Harms, H.; Müller, R. H. Exploiting mixtures of H2, CO2, and O2 for improved production of methacrylate precursor 2-hydroxyisobutyric acid by engineered Cupriavidus necator strains. Appl. Microbiol. Biotechnol. 2015, 99 (5), 2131-2145.
- Lee, J.; Jung, Y.; Park, J. Y.; Lee, S. H.; Ryu, D. H.; Hwang, G. S. LC/MS-based polar metabolite profiling reveals gender differences in serum from patients with myocardial infarction. J. Pharm. Biomed. Anal. 2015, 115, 475-486.