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Thermo Scientific Chemicals
Ethyl picolinate, 99%
CAS: 2524-52-9 | C8H9NO2 | 151.17 g/mol
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Catalog number A13973.30
also known as A13973-30
Price (JPY)Request A Quote
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Quantity:
250 g
Chemical Identifiers
CAS2524-52-9
IUPAC Nameethyl pyridine-2-carboxylate
Molecular FormulaC8H9NO2
InChI KeyFQYYIPZPELSLDK-UHFFFAOYSA-N
SMILESCCOC(=O)C1=CC=CC=N1
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Specifications
Specification Sheet
Specification SheetFormLiquid
Appearance (Color)Clear colorless to pale yellow
Assay (GC)≥98.5%
Refractive Index1.5090-1.5120 @ 20?C
Ethyl picolinate is used in the preparation of 2-Aminodihydro[1,3]thiazines as BACE 2 inhibitors which is used in the treatment of diabetes. It is also used as pharmaceutical intermediate.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Ethyl picolinate is used in the preparation of 2-Aminodihydro[1,3]thiazines as BACE 2 inhibitors which is used in the treatment of diabetes. It is also used as pharmaceutical intermediate.
Solubility
Fully miscible in water.
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
Ethyl picolinate is used in the preparation of 2-Aminodihydro[1,3]thiazines as BACE 2 inhibitors which is used in the treatment of diabetes. It is also used as pharmaceutical intermediate.
Solubility
Fully miscible in water.
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- David S.Sigman; Catherine T.Jorgensen. Models for metalloenzymes. Zinc (II)-catalyzed transesterification of N-(.beta.-hydroxyethyl)ethylenediamine by p-nitrophenyl picolinate. J. Am. Chem. Soc. 1972, 94,(5), 1724-1730.
- Jennifer Lafont; Adolfo Ensuncho; Rosa M.Dominguez; Alexandra Rotinov; Armando Herize; Jairo Quijano; Gabriel Chuchani. Mechanism of elimination of amino acid derivatives in the gas phase. Pyrolysis kinetics of ethyl picolinate, ethyl 1-methylpipecolinate and picolinic acid. Journal of Physical Organic Chemistry. 2003, 16,(1), 84-88.