1-Bromo-3-phenylpropane is used in the synthesis of MraY natural inhibitors as antibacterial agents. Also used in the preparation of quinolinone derivatives as potent and selective MAO-B inhibitors.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
1-Bromo-3-phenylpropane is used in the synthesis of MraY natural inhibitors as antibacterial agents. Also used in the preparation of quinolinone derivatives as potent and selective MAO-B inhibitors.
Solubility
Soluble in water (partly). Soluble in chloroform and methanol.
Notes
Store in cool, dry place in tightly closed containers. Store away from oxidizing agent.
RUO – Research Use Only
General References:
- Aloke K. Dutta; Cen Xu; and Maarten E. A. Reith. Structure-Activity Relationship Studies of Novel 4-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-1-(3-phenylpropyl)piperidine Analogs: Synthesis and Biological Evaluation at the Dopamine and Serotonin Transporter Sites. J. Med. Chem. 1996, 39(3), 749-756.
- Maw-Ling Wang; Chau-Je Chen. Kinetic Study of Synthesizing 1-(3-Phenylpropyl)pyrrolidine-2,5-dione under Solid-Liquid Phase-Transfer Catalytic Conditions Assisted by Ultrasonic Irradiation. Org. Process Res. Dev. 2010, 14(3), 737-745.