5-Iodouracil, 97%
5-Iodouracil, 97%
5-Iodouracil, 97%
Thermo Scientific Chemicals

5-Iodouracil, 97%

CAS: 696-07-1 | C4H3IN2O2 | 237.98 g/mol
Quantity:
10 g
50 g
Catalog number A18994.18
also known as A18994-18
Price (JPY)
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Quantity:
50 g
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Chemical Identifiers
CAS696-07-1
IUPAC Name5-iodo-1,2,3,4-tetrahydropyrimidine-2,4-dione
Molecular FormulaC4H3IN2O2
InChI KeyKSNXJLQDQOIRIP-UHFFFAOYSA-N
SMILESIC1=CNC(=O)NC1=O
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SpecificationsSpecification SheetSpecification Sheet
FormPowder
Appearance (Color)White to pale cream
Assay (Aqueous acid-base Titration)≥96.0 to ≤104.0%
It is used as an intermediate. It has an antitumor activity.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used as an intermediate. It has an antitumor activity.

Solubility
Very faint turbidity in NH3aq. Soluble in 1M NaOH.

Notes
Light Sensitive. Store away from oxidizing agents and light. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only

General References:

  1. Morris J. Robins.; Philip J. Barr.Nucleic acid related compounds. 31. Smooth and efficient palladium-copper catalyzed coupling of terminal alkynes with 5-iodouracil nucleosides.Tetrahedron Lett.198122(5), 421-424.
  2. MC Willis.; BJ Hicke.; OC Uhlenbeck.; TR Cech.; TH Koch. Photocrosslinking of 5-iodouracil-substituted RNA and DNA to proteins.Science.1993,262(5137), 1255-1257.
  3. For a review of the use of uracils as starting materials in heterocyclic synthesis, see: Adv. Het. Chem., 55, 130 (1992).