Invitrogen™

PIK3CB/PIK3R2 (p110 beta/p85 beta) Recombinant Human Protein

Catalog number: A32910
Invitrogen™

PIK3CB/PIK3R2 (p110 beta/p85 beta) Recombinant Human Protein

Catalog number: A32910
Catalog Number
A32910
Unit Size
100 µg
Price (USD)
2,115.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
20 µg
Price (USD)
732.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
1 mg
Price (USD)
6,570.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
A32910100 µg
2,115.00
Your Price:
***
A3108420 µg
732.00
Your Price:
***
A333951 mg
6,570.00
Your Price:
***
Product Overview
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This PIK3CB/PIK3R2 (p110 beta/p85 beta) recombinant human protein (full length) was expressed in insect cells. PIK3CB/PIK3R2 lipid kinase (p110 beta/p85 beta) or Phosphatidylinositol 3-kinase (PI3K) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids which functions in signaling pathways that regulate cell growth by virtue of their activation in response to various mitogenic stimuli. PI3Ks are composed of a 110-kDa catalytic subunit and a 85-kDa adaptor subunit. PIK3CB plays a critical role in regulating the formation and stability of alpha-2B-beta-3 integrin adhesion bonds, which are necessary for shear force-induced platelet activation. PIK3CB sustains alpha-2B-beta-3 integrin activation and stabilized platelet aggregation by regulating both integrin-dependent calcium flux and Gi activation of RAP1B. PIK3CB/PIK3R2 (p110 beta/p85 beta) recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the Adapta™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
PIK3CB: NP_006210.1, PIK3R2: NP_005018.1
Shipping Condition
Dry Ice
Expression System
Insect
Form
Liquid
Protein Form
Full Length, Recombinant, Active
Species
Human
Validated Application
Kinase Assay
Molecular Weight
123.7/83.5 kDa
Quantity
100 µg
KinaseFamily
PI3 Kinase
Protein Length
Full Length
Recombinant
Yes
Protein Tag
His Tag

Contents & Storage

Storage Buffer: 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol.

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