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Invitrogen
FCN1 Monoclonal Antibody (1)
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Product Details
ABS 036-01-02
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
1
Immunogen
Purified recombinant protein corresponding to residues 95-314 of human M-Ficolin, expressed in prokaryote.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.08 mg/mL
Amount
432 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
15mM sodium azide
Storage conditions
4°C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
ABS 036-01-02 detects M-Ficolin from human samples.
ABS 036-01-02 has been successfully used in ELISA and IHC procedures.
The ABS 036-01-02 immunogen is purified recombinant protein corresponding to residues 95-314 of human M-Ficolin, expressed in prokaryote.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
Target Information
M-Ficolin (Ficolin-1) is a non-serum protein that is expressed in leukocytes and lung. M-Ficolin precipitates with mannose-binding lectin (MBL)-associated serine proteases (MASP)-1 and MASP-2, indicating that M-Ficolin forms complexes with MASP-1 and MASP-2, recognizes certain types of bacteria and subsequently activates the lectin pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Collagen/fibrinogen domain-containing protein 1; ficolin (collagen/fibrinogen domain-containing) 1; Ficolin-1; Ficolin-A; Ficolin-alpha; M-ficolin; unnamed protein product
Gene Aliases: FCN1; FCNM
UniProt ID: (Human) O00602
Entrez Gene ID: (Human) 2219
complement activation, lectin pathway
activation of membrane attack complex
immune system process
cell surface pattern recognition receptor signaling pathway
proteolysis
complement activation
G-protein coupled receptor signaling pathway
opsonization
zymogen activation
killing of cells of other organism
positive regulation of interleukin-8 production
protein localization to cell surface
recognition of apoptotic cell
innate immune response
negative regulation of viral entry into host cell
protein maturation
positive regulation of opsonization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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