4-Amino-5-bromopyrimidine, 98%
4-Amino-5-bromopyrimidine, 98%
4-Amino-5-bromopyrimidine, 98%
4-Amino-5-bromopyrimidine, 98%
Thermo Scientific Chemicals

4-Amino-5-bromopyrimidine, 98%

CAS: 1439-10-7 | C4H4BrN3 | 174.001 g/mol
Quantity:
1 g
5 g
Catalog number H64335.03
also known as H64335-03
Price (JPY)
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1 g
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Chemical Identifiers
CAS1439-10-7
IUPAC Name5-bromopyrimidin-4-amine
Molecular FormulaC4H4BrN3
InChI KeyIIFAONYUCDAVGA-UHFFFAOYSA-N
SMILESNC1=NC=NC=C1Br
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SpecificationsSpecification SheetSpecification Sheet
Assay (HPLC)≥97.5%
FormPowder or crystalline powder
Appearance (Color)Yellow to yellow-green or cream to pale brown
It is an inhibitor of thymidine phosphorylase, an enzyme known to be over-expressed in several tumor types and to play a role in metastasis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is an inhibitor of thymidine phosphorylase, an enzyme known to be over-expressed in several tumor types and to play a role in metastasis.

Solubility
Slightly soluble in water.

Notes
Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.
RUO – Research Use Only

General References:

  1. Thomas J. Kress; and Larry L. Moore. Studies on the bromination of pyrimidine. A facile synthesis of 5-bromopyrimidine. Journal of Heterocyclic Chemistry.198910 (2), 153-157.
  2. E. Kalatzis. Kinetics of the hydrolytic deamination of N-heteroaromatic amines in aqueous alkaline solutions. J. Chem. Soc. B.1969 (0), 96-104.