It is an inhibitor of thymidine phosphorylase, an enzyme known to be over-expressed in several tumor types and to play a role in metastasis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It is an inhibitor of thymidine phosphorylase, an enzyme known to be over-expressed in several tumor types and to play a role in metastasis.
Solubility
Slightly soluble in water.
Notes
Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.
RUO – Research Use Only
General References:
- Thomas J. Kress; and Larry L. Moore. Studies on the bromination of pyrimidine. A facile synthesis of 5-bromopyrimidine. Journal of Heterocyclic Chemistry.198910 (2), 153-157.
- E. Kalatzis. Kinetics of the hydrolytic deamination of N-heteroaromatic amines in aqueous alkaline solutions. J. Chem. Soc. B.1969 (0), 96-104.