Search Thermo Fisher Scientific
Element Search
Structure SearchThermo Scientific Chemicals
Paclitaxel, 99.5+%, Thermo Scientific Chemicals
Catalog number: J62734.03
1 g, Each
Thermo Scientific Chemicals
Paclitaxel, 99.5+%, Thermo Scientific Chemicals
Catalog number: J62734.03
1 g, Each
Quantity
Catalog number: J62734.03
Price (USD)
Price: 727.00
Online price: 617.65
Your price:
Quantity
-
Chemical Identifiers
CAS
33069-62-4
IUPAC Name
(1S,2S,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0³,¹⁰.0⁴,⁷]heptadec-13-en-2-yl benzoate
Molecular Formula
C47H51NO14
InChI Key
RCINICONZNJXQF-VAZQATRQSA-N
SMILES
CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)C3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1
Specifications
Specification SheetAppearance (Color)
White to cream
Assay from Suppliers CofA
≥99.5% (HPLC)
Form
Crystalline powder or granular
Description
Promotes assembly and inhibits disassembly of microtubules (anti-cancer agent)Paclitaxel is widely used in chemotherapeutic compound. It is used to treat certain types of cancer such as ovarian cancer, breast cancer, lung cancer and pancreatic cancer among others. It interferes with the growth of cancer cells and slows down their growth and spread in the body. It is also used to treat AIDS-related Kaposi's sarcoma.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Paclitaxel is a tetracyclic diterpenoid isolated from the Pacific yew, Taxus brevifolia
- Paclitaxel acts as an antineoplastic agent by binding tubulin and preventing cell division
- Paclitaxel may also bind Bcl-2 and lead to disinhibition of apoptosis
Application
- Paclitaxel is used in the study of lung, breast, and ovarian cancers; it may be useful in the research of other cancer types
- It is suitable for cell culture, biochemistry, and molecular biology applications
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
RUO – Research Use Only
Figures
Documents & Downloads
Certificates
Search by lot number or partial lot number
Frequently asked questions (FAQs)
Citations & References
Search citations by name, author, journal title or abstract text