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Thermo Scientific Chemicals
Spermine tetrahydrochloride, 99%
Binds to the polyamine modulatory site of NMDA | CAS: 306-67-2 | C10H30Cl4N4 | 348.18 g/mol
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Catalog number J63060.14
also known as J63060-14
Price (JPY)Request A Quote
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Quantity:
25 g
Chemical Identifiers
CAS306-67-2
IUPAC Nametetrahydrogen (3-aminopropyl)({4-[(3-aminopropyl)amino]butyl})amine tetrachloride
Molecular FormulaC10H30Cl4N4
InChI KeyXLDKUDAXZWHPFH-UHFFFAOYSA-N
SMILES[H+].[H+].[H+].[H+].[Cl-].[Cl-].[Cl-].[Cl-].NCCCNCCCCNCCCN
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Specifications
Specification Sheet
Specification SheetFormCrystalline powder
Water Content (Karl Fischer Titration)≤ 1.0%
pH5.0 to 7.5
Appearance (Color)White to pale cream
Assay from Supplier's CofA≥98.5 to ≤101.5% (Acid Titration)
Spermine tetrahydrochloride, is used to precipitate DNA from low salt aqueous buffers. Spermine tetrahydrochloride was used to precipitate DNA for flow cytometric analysis from fresh frozen breast cancer tissue, archival tissue of salivary gland, renal and thyroid tumors2 and red blood cells of chicken.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Spermine tetrahydrochloride, is used to precipitate DNA from low salt aqueous buffers. Spermine tetrahydrochloride was used to precipitate DNA for flow cytometric analysis from fresh frozen breast cancer tissue, archival tissue of salivary gland, renal and thyroid tumors2 and red blood cells of chicken.
Solubility
Soluble in water (348.2 g/L at 20°C).
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Hygroscopic. Store under inert gas. Keep away from strong oxidizing agents.
Spermine tetrahydrochloride, is used to precipitate DNA from low salt aqueous buffers. Spermine tetrahydrochloride was used to precipitate DNA for flow cytometric analysis from fresh frozen breast cancer tissue, archival tissue of salivary gland, renal and thyroid tumors2 and red blood cells of chicken.
Solubility
Soluble in water (348.2 g/L at 20°C).
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Hygroscopic. Store under inert gas. Keep away from strong oxidizing agents.
RUO – Research Use Only
General References:
- Benveniste and Mayer. Multiple effects of spermine on N-methyl-D-aspartic acid receptor responses of rat cultured hippocampal neurones. J.Physiol. 1993, 464, (2), 131-63.
- Munir et al. Polyamines modulate the neurotoxic effects of NMDA in vivo. Brain Res. 1993, 616, (1-2), 163-70.