5-Nitrothiophene-2-carboxaldehyde, 98%
5-Nitrothiophene-2-carboxaldehyde, 98%
5-Nitrothiophene-2-carboxaldehyde, 98%
5-Nitrothiophene-2-carboxaldehyde, 98%
Thermo Scientific Chemicals

5-Nitrothiophene-2-carboxaldehyde, 98%

CAS: 4521-33-9 | C5H3NO3S | 157.143 g/mol
Quantity:
5 g
25 g
Catalog number L01493.06
also known as L01493-06
Price (JPY)
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5 g
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Chemical Identifiers
CAS4521-33-9
IUPAC Name5-nitrothiophene-2-carbaldehyde
Molecular FormulaC5H3NO3S
InChI KeyCHTSWZNXEKOLPM-UHFFFAOYSA-N
SMILES[O-][N+](=O)C1=CC=C(S1)C=O
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)Cream to yellow to green to brown to gray
Assay (GC)≥97.5%
FormCrystals or powder or crystalline powder or lumps or fused solid or needles
Free acid (titration)≤1.5%
5-Nitrothiophene-2-carboxaldehyde is used as a chemical for protoemics research as well as the synthesis of 2,3-dihydro-2-(5-nitro-2-thienyl) quinazolin-4-(1H)-ones1 and various novel oxime ether derivatives which are anti-protozoan agents.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
5-Nitrothiophene-2-carboxaldehyde is used as a chemical for protoemics research as well as the synthesis of 2,3-dihydro-2-(5-nitro-2-thienyl) quinazolin-4-(1H)-ones1 and various novel oxime ether derivatives which are anti-protozoan agents.

Solubility
Insoluble in water.

Notes
Air Sensitive. Keep container tightly closed. Store away from oxidizing agents.
RUO – Research Use Only

General References:

  1. Alireza Foroumadi.; Zahra Kiani.; Fatemeh Soltani. Antituberculosis agents VIII: Synthesis and in vitro antimycobacterial activity of alkyl α-[5-(5-nitro-2-thienyl)-1,3,4-thiadiazole-2-ylthio]acetates. Il Farmaco. 2003, 58, (11), 1073-1076.
  2. Shailendra Singh.; Fareeda Athar.; Amir Azam. Synthesis, spectral studies and in vitro assessment for antiamoebic activity of new cyclooctadiene ruthenium(II) complexes with 5-nitrothiophene-2-carboxaldehyde thiosemicarbazones. Bioorganic & Medicinal Chemistry Letters. 2005, 15, (24), 5424-5428.