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Invitrogen
MAD2 Monoclonal Antibody (17D10)
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Product Details
MA1-5832
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
17D10
Immunogen
Recombinant human Mad2L1
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Western blot detects a band of approximately 25 kDa (predicted molecular weight: 24.6 kDa).
Target Information
Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HsMAD2; MAD2; MAD2 (mitotic arrest deficient, yeast, homolog)-like 1; MAD2 mitotic arrest deficient-like 1; MAD2-like 1; MAD2-like protein 1; MadL1; Mitotic arrest deficient 2-like protein 1; mitotic arrest deficient, yeast, homolog-like 1; Mitotic spindle assembly checkpoint protein MAD2A; unnamed protein product
Gene Aliases: HSMAD2; MAD2; MAD2L1
UniProt ID: (Human) Q13257
Entrez Gene ID: (Human) 4085
mitotic sister chromatid segregation
establishment of mitotic spindle orientation
mitotic spindle assembly checkpoint
negative regulation of protein catabolic process
negative regulation of mitotic cell cycle
cell division
establishment of centrosome localization
regulation of nuclear division
positive regulation of mitotic cell cycle spindle assembly checkpoint
negative regulation of mitotic cell cycle phase transition
negative regulation of ubiquitin protein ligase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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