Search
Invitrogen
ALOX15 Monoclonal Antibody (OTI3G8)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
MA5-25853
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Published species
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
OTI3G8
Immunogen
Full length human recombinant protein of ALOX15 produced in HEK293T cell
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
ALOX15 converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid. The protein also acts on C-12 of arachidonate as well as on linoleic acid.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 12-LOX; 12/15-lipoxygenase; 12/15-LOX; 15-lipooxygenase-1; 15-lipoxygenase; 15-lipoxygenase type 1; 15-LOX; 15-LOX type 1; 15-LOX2; Arachidonate 12-lipoxygenase, leukocyte-type; Arachidonate 15-lipoxygenase; Arachidonate omega-6 lipoxygenase; Hepoxilin A3 synthase Alox15; Linoleate 13S-lipoxygenase; Polyunsaturated fatty acid lipoxygenase ALOX15; unnamed protein product
Gene Aliases: 12-LOX; 15-LOX; 15-LOX-1; Alox12; Alox12l; ALOX15; LOG15
UniProt ID: (Human) P16050, (Rat) Q02759
Entrez Gene ID: (Human) 246, (Rat) 81639
arachidonate 12-lipoxygenase activity
iron ion binding
protein binding
phosphatidylinositol-4,5-bisphosphate binding
lipid binding
linoleate 13S-lipoxygenase activity
oxidoreductase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
metal ion binding
arachidonate 15-lipoxygenase activity
dioxygenase activity
potassium channel inhibitor activity
hepoxilin-epoxide hydrolase activity
hepoxilin A3 synthase activity
oxygenase
ossification
negative regulation of adaptive immune response
lipid metabolic process
fatty acid metabolic process
phosphatidylethanolamine biosynthetic process
inflammatory response
positive regulation of cell-substrate adhesion
arachidonic acid metabolic process
lipoxygenase pathway
fatty acid oxidation
bone mineralization
positive regulation of actin filament polymerization
lipid oxidation
response to endoplasmic reticulum stress
regulation of peroxisome proliferator activated receptor signaling pathway
cellular response to interleukin-13
wound healing
long-chain fatty acid biosynthetic process
apoptotic cell clearance
linoleic acid metabolic process
regulation of inflammatory response
hepoxilin biosynthetic process
positive regulation of ERK1 and ERK2 cascade
cellular response to calcium ion
regulation of engulfment of apoptotic cell
lipoxin A4 biosynthetic process
positive regulation of cell proliferation
positive regulation of cell growth
positive regulation of heterotypic cell-cell adhesion
regulation of membrane potential
negative regulation of apoptotic process
negative regulation of cell volume
icosanoid biosynthetic process
oxidation-reduction process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support