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          • Primary Antibodies ›
          • PHPT1 Antibodies

          Invitrogen

          PHPT1 Monoclonal Antibody (01)

          View all (23) PHPT1 antibodies

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          Cite PHPT1 Monoclonal Antibody (01)

          Additional Information:
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          PHPT1 Monoclonal Antibody (01)

          Product Details

          MA5-30745

          Applications
          Tested Dilution
          Publications

          ELISA (ELISA)

          1:1,000-1:2,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Mouse / IgG1

          Class

          Monoclonal

          Type

          Antibody

          Clone

          01

          Immunogen

          Recombinant Human PHPT1 protein (Ala2-Tyr125)
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Protein A

          Storage buffer

          PBS

          Contains

          no preservative

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2786433

          Product Specific Information

          This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).

          This antibody has specificity for Human PHPT1.

          Target Information

          The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: 14 kDa phosphohistidine phosphatase; epididymis secretory sperm binding protein Li 132P; JANA; Phosphohistidine phosphatase 1; PHP; PHP14; PHPT1; Protein histidine phosphatase; Protein janus-A homolog; PTP-H1; PTPH1; sex-regulated protein janus-a

          View more View less

          Gene Aliases: CGI-202; HEL-S-132P; HSPC141; PHP; PHP14; PHPT1

          View more View less

          UniProt ID: (Human) Q9NRX4

          View more View less

          Entrez Gene ID: (Human) 29085

          View more View less

          Function(s)
          phosphoprotein phosphatase activity enzyme inhibitor activity protein binding hydrolase activity calcium channel inhibitor activity ion channel binding actin filament binding protein histidine phosphatase activity
          Process(es)
          actin cytoskeleton organization positive regulation of insulin secretion involved in cellular response to glucose stimulus negative regulation of T cell receptor signaling pathway lamellipodium organization positive regulation of cell motility
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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