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Invitrogen

C/EBP beta Recombinant Rabbit Monoclonal Antibody (SC55-05)

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C/EBP beta Recombinant Rabbit Monoclonal Antibody (SC55-05)

Product Details

MA5-32252

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunocytochemistry (ICC/IF)

1:100
-

Flow Cytometry (Flow)

1:50-1:100
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

SC55-05

Immunogen

Synthetic peptide within Rat C/EBP Beta aa 248-297.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Protein A

Storage buffer

TBS, pH 7.4, with 40% Glycerol, 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2809538

Product Specific Information

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Target Information

This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: AGP/EBP; C EBP; C/EBP BETA; C/EBP-related protein 2; CCAAT/enhancer binding protein (C/EBP), beta; CCAAT/enhancer-binding protein beta; IL-6DBP; interleukin 6-dependent DNA-binding protein; Interleukin-6-dependent-binding protein; LAP; LIP; Liver activator protein; Liver-enriched inhibitory protein; Liver-enriched transcriptional activator; Nuclear factor NF-IL6; nuclear factor of interleukin 6; nuclear factor-IL6; nuclear protein Il6; OTTMUSP00000017503; SF-B; Silencer factor B; TCF-5; Transcription factor 5; transcription factor C/EBP beta; unnamed protein product

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Gene Aliases: C/EBP-beta; C/EBPbeta; CEBPB; CRP2; IL-6DBP; IL6DBP; LAP; LIP; NF-IL6; NF-M; Nfil6; PP9092; Sfb; TCF5

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UniProt ID: (Human) P17676, (Mouse) P28033, (Rat) P21272

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Entrez Gene ID: (Human) 1051, (Mouse) 12608, (Rat) 24253

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Function(s)
transcription regulatory region sequence-specific DNA binding RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding kinase binding chromatin DNA binding histone acetyltransferase binding glucocorticoid receptor binding identical protein binding protein homodimerization activity histone deacetylase binding sequence-specific DNA binding ubiquitin-like protein ligase binding protein heterodimerization activity RNA polymerase II sequence-specific DNA binding transcription factor binding DNA-binding transcription factor binding sequence-specific double-stranded DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding transcription factor binding basic leucine zipper transcription factor
Process(es)
negative regulation of transcription from RNA polymerase II promoter ovarian follicle development liver development embryonic placenta development granuloma formation transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter acute-phase response inflammatory response immune response memory positive regulation of gene expression cell differentiation neuron differentiation response to lipopolysaccharide regulation of interleukin-6 production positive regulation of interleukin-4 production mammary gland epithelial cell proliferation response to endoplasmic reticulum stress T-helper 1 cell activation negative regulation of T cell proliferation defense response to bacterium negative regulation of neuron apoptotic process fat cell differentiation regulation of cell differentiation positive regulation of fat cell differentiation positive regulation of osteoblast differentiation regulation of osteoclast differentiation negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of inflammatory response brown fat cell differentiation mammary gland epithelial cell differentiation myeloid cell development intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress positive regulation of biomineral tissue development cellular response to lipopolysaccharide cellular response to amino acid stimulus cellular response to interleukin-1 hepatocyte proliferation liver regeneration positive regulation of cold-induced thermogenesis integrated stress response signaling regulation of odontoblast differentiation positive regulation of sodium-dependent phosphate transport regulation of dendritic cell differentiation regulation of interleukin-6 biosynthetic process regulation of transcription involved in cell fate commitment positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
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