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Invitrogen
ABCE1 Recombinant Rabbit Monoclonal Antibody (1N4I7)
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Product Details
MA5-35761
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
1N4I7
Immunogen
Synthetic peptide
Conjugate
Form
Liquid
Concentration
1.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 2'-5'-oligoadenylate-binding protein; ABC 38; ABCE 1; ATP-binding cassette sub-family E member 1; ATP-binding cassette, sub-family E (OABP), member 1; ATP-binding cassette, subfamily E, member 1; HP68; HuHP68; Ribonuclease 4 inhibitor; ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) inhibitor; ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) inhibitor; RNase 4 inhibitor; RNase L inhibitor; RNase L inhibitor 1; RNS4I; RNS4l (Eye)
Gene Aliases: ABC38; ABCE1; C79080; OABP; OK/SW-cl.40; RLI; RLI1; RNASEL1; RNASELI; RNS41; RNS4I
UniProt ID: (Human) P61221, (Mouse) P61222
Entrez Gene ID: (Human) 6059, (Mouse) 24015
nucleotide binding
GTPase activity
iron ion binding
protein binding
ATP binding
hydrolase activity
ATPase activity
nucleoside-triphosphatase activity
ribosomal small subunit binding
CTPase activity
metal ion binding
iron-sulfur cluster binding
4 iron, 4 sulfur cluster binding
endoribonuclease inhibitor activity
translation
translational initiation
translational termination
regulation of translation
ribosome disassembly
regulation of macromolecule metabolic process
negative regulation of endoribonuclease activity
protein ufmylation
rescue of stalled ribosome
CAT tailing
ribosome-associated ubiquitin-dependent protein catabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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