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Invitrogen
CNOT8 Recombinant Rabbit Monoclonal Antibody (HL2586)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-56655
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat,
Zebrafish
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL2586
Immunogen
Recombinant fragment of human CNOT8.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Target Information
CNOT8 (CCR4-NOT transcription complex subunit 8), also known as CALIF or POP2, is a 292 amino acid protein that localizes to both the nucleus and the cytoplasm and functions as part of the CCR-NOT complex. Expressed ubiquitously, CNOT8 plays a role in transcriptional regulation for a diverse set of processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CAF1-like protein; CAF1-like protein; CCR4-NOT complex subunit; CAF2; CALIFp; CCR4-associated factor 8; h CAF1-like protein; PGK promoter directed over production; unnamed protein product
Gene Aliases: 1500015I04Rik; 1810022F04Rik; CAF1; Caf1b; CALIF; hCAF1; POP2; wu:fe49a05; zgc:63844
UniProt ID: (Human) Q9UFF9, (Mouse) Q9D8X5
Entrez Gene ID: (Human) 9337, (Mouse) 69125, (Rat) 363603, (Zebrafish) 406788
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
nuclear-transcribed mRNA poly(A) tail shortening
positive regulation of cell proliferation
mRNA cleavage involved in gene silencing by miRNA
positive regulation of mRNA catabolic process
biological_process
transcription, DNA-templated
negative regulation of translation
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
neuron development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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