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          • Primary Antibodies ›
          • alpha-1 Microglobulin Antibodies

          Invitrogen

          alpha-1 Microglobulin Polyclonal Antibody

          View all (35) alpha-1 Microglobulin antibodies

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          Cite alpha-1 Microglobulin Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (4)
          alpha-1 Microglobulin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          alpha-1 Microglobulin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          alpha-1 Microglobulin Antibody (PA5-51589) in IHC (P)

          Immunohistochemical analysis of alpha-1 Microglobulin in human colon using alpha-1 Microglobulin Polyclonal Antibody (Product # PA5-51589) shows no cytoplasmic positivity in glandular cells as expected. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          alpha-1 Microglobulin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          alpha-1 Microglobulin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          alpha-1 Microglobulin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          alpha-1 Microglobulin Antibody in Immunohistochemistry (IHC)
          alpha-1 Microglobulin Polyclonal Antibody

          Product Details

          PA5-51589

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:500
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human alpha-1 Microglobulin. Recombinant protein control fragment (Product #RP-100509).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Amount

          10 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2637883

          Product Specific Information

          Immunogen sequence: VLPQEEEGSG GGQLVTEVTK KEDSCQLGYS AGPCMGMTSR YFYNGTSMAC ETFQYGGCMG NGNNFVTEKE CLQTCRTVAA CNLPIVRGPC RAFIQLWAFD AVKGKCVLFP YGGCQGNGNK FYSEKECRE

          Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 77%.

          Target Information

          This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: AMBP protein; bikunin; complex-forming glycoprotein heterogeneous in charge; GIG19; growth-inhibiting protein 19; inter-alpha-trypsin inhibitor light chain; Protein AMBP; Protein HC; Protein Protein HC; trypstatin; unnamed protein product; uristatin; uronic-acid-rich protein

          View more View less

          Gene Aliases: A1M; AMBP; EDC1; HCP; HI30; IATIL; ITI; ITIL; ITILC; UTI

          View more View less

          UniProt ID: (Human) P02760

          View more View less

          Entrez Gene ID: (Human) 259

          View more View less

          Function(s)
          serine-type endopeptidase inhibitor activity protein binding antioxidant activity oxidoreductase activity oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor calcium channel inhibitor activity IgA binding heme binding carbohydrate binding peptidase inhibitor activity chondroitin sulfate binding protein homodimerization activity calcium oxalate binding collagen fibril binding
          Process(es)
          cell adhesion female pregnancy hemoglobin metabolic process protein catabolic process cellular response to reactive oxygen species heme catabolic process negative regulation of JNK cascade negative regulation of immune response cellular oxidant detoxification cytochrome c metabolic process
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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