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Invitrogen
Sorbitol Dehydrogenase Polyclonal Antibody
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FIGURE: 1 / 9
Sorbitol Dehydrogenase Antibody (PA5-59228) in IHC
Immunohistochemical staining of Sorbitol Dehydrogenase in human kidney, liver, skeletal muscle and thyroid gland using Sorbitol Dehydrogenase Polyclonal Antibody (Product # PA5-59228) (A) shows similar protein distribution across tissues to an independent Sorbitol Dehydrogenase Polyclonal Antibody (B).
Product Details
PA5-59228
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SorD. Recombinant protein control fragment (Product #RP-98093).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PGDRVAIEPG APRENDEFCK MGRYNLSPSI FFCATPPDDG NLCRFYKHNA AFCYKLPDNV TFEEGALIEP LSVGIHACRR GG
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 89%.
Target Information
Sorbitol dehydrogenase catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NADcofactor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: (R,R)-butanediol dehydrogenase; epididymis secretory sperm binding protein Li 95n; L-iditol 2-dehydrogenase; Polyol dehydrogenase; RDH; Ribitol dehydrogenase; SDH; Sorbitol dehydrogenase; sorbitol dehydrogenase 1; SORD 1; XDH; Xylitol dehydrogenase
Gene Aliases: HEL-S-95n; Sdh-1; Sdh1; Sodh-1; SORD; SORD1
UniProt ID: (Human) Q00796, (Rat) P27867, (Mouse) Q64442
Entrez Gene ID: (Human) 6652, (Rat) 24788, (Mouse) 20322
glucose metabolic process
sorbitol catabolic process
response to osmotic stress
response to hormone
glucuronate catabolic process to xylulose 5-phosphate
sperm motility
response to nutrient levels
response to drug
fructose biosynthetic process
response to cadmium ion
response to copper ion
L-xylitol catabolic process
L-xylitol metabolic process
oxidation-reduction process
sorbitol metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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