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Invitrogen
CD300f Polyclonal Antibody
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FIGURE: 1 / 1
CD300f Antibody (PA5-109496) in WB
Western blot analysis of CD300f in extracts of various cell lines. Samples were incubated with CD300f Polyclonal antibody (Product # PA5-109496) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-109496
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 23-150 of human CD300LF (NP_001276011.1).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.81 mg/mL
Amount
181 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TQITGPTTVN GLERGSLTVQ CVYRSGWETY LKWWCRGAIW RDCKILVKTS GSEQEVKRDR VSIKDNQKNR TFTVTMEDLM KTDADTYWCG IEKTGNDLGV TVQVTIDPAP VTQEETSSSP TLTGHHLD
Target Information
CLM1 is an inhibitory receptor of the Ig superfamily expressed on myeloid cells. It mediates negative regulatory signals by recruiting SHP1 (PTPN6; MIM 176883) or SHIP.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD300 antigen-like family member F; CD300f; CLM-1; CMRF35-like molecule 1; IgSF13; immune receptor; Immune receptor expressed on myeloid cells 1; immunoglobin superfamily member 13; Immunoglobulin superfamily member 13; inhibitory receptor IREM1; IREM-1; IREM-1 Sv1; IREM-1 Sv2; NK inhibitory receptor; NKIR; unnamed protein product
Gene Aliases: CD300F; CD300LF; CLM-1; CLM1; IGSF13; IREM-1; IREM1; LMIR3; NKIR; UNQ3105/PRO10111
UniProt ID: (Human) Q8TDQ1
Entrez Gene ID: (Human) 146722
immune system process
immune response-activating signal transduction
negative regulation of mast cell activation
negative regulation of MyD88-dependent toll-like receptor signaling pathway
TRIF-dependent toll-like receptor signaling pathway
interleukin-13-mediated signaling pathway
positive regulation of interleukin-4-mediated signaling pathway
negative regulation of apoptotic cell clearance
positive regulation of apoptotic cell clearance
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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