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Invitrogen
MYST2 Polyclonal Antibody
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FIGURE: 1 / 6
MYST2 Antibody (PA5-120952) in IHC (P)
Immunohistochemistry analysis of MYST2 in paraffin-embedded human breast cancer using. Samples were incubated with MYST2 Polyclonal antibody (Product # PA5-120952) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-120952
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 55-193 of human KAT7 (NP_008998.1).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.85 mg/mL
Amount
85 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive test controls include: BT-474, HepG2, 293T, HeLa. The target is usually found in the following locations: Nucleus, nucleoplasm.
Immunogen sequence: DSSPVRNLQS FGTEEPAYST RRVTRSQQQP TPVTPKKYPL RQTRSSGSET EQVVDFSDRE TKNTADHDES PPRTPTGNAP SSESDIDISS PNVSHDESIA KDMSLKDSGS DLSHRPKRRR FHESYNFNMK CPTPGCNSL
Target Information
This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. This gene was thought initially to be located on chromosome X, however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC 2.3.1.48; HBO1; histone acetyltransferase binding to ORC1; histone acetyltransferase MYST2; K (lysine) acetyltransferase 7; K(lysine) acetyltransferase 7; lysine acetyltransferase 7; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; MYST family member; MYST histone acetyltransferase 2; MYST protein 2; MYST-2; unnamed protein product
Gene Aliases: HBO1; HBOA; MYST2; ZC2HC7
UniProt ID: (Human) O95251, (Mouse) Q5SVQ0, (Rat) Q810T5
Entrez Gene ID: (Human) 11143, (Mouse) 217127, (Rat) 303470
chromatin binding
DNA replication origin binding
transcription cofactor activity
histone acetyltransferase activity
protein binding
zinc ion binding
H3 histone acetyltransferase activity
H4 histone acetyltransferase activity
histone acetyltransferase activity (H3-K14 specific)
histone acetyltransferase activity (H3-K23 specific)
histone acetyltransferase activity (H4-K5 specific)
histone acetyltransferase activity (H4-K8 specific)
histone acetyltransferase activity (H4-K12 specific)
histone acetyltransferase activity (H3-K4 specific)
histone acetyltransferase activity (H4-K16 specific)
peptide-lysine-N-acetyltransferase activity
regulation of cell growth
natural killer cell differentiation
regulation of DNA replication
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
internal peptidyl-lysine acetylation
regulation of DNA-dependent DNA replication initiation
T cell differentiation
stress-activated protein kinase signaling cascade
positive regulation of DNA-templated transcription, elongation
positive regulation of erythrocyte differentiation
positive regulation of DNA replication
positive regulation of gene expression, epigenetic
positive regulation of transcription from RNA polymerase II promoter
regulation of cell cycle
response to sorbitol
response to hydroxyurea
response to actinomycin D
response to dithiothreitol
response to anisomycin
DNA replication-dependent chromatin disassembly
positive regulation of protein localization to nucleus
positive regulation of hematopoietic stem cell proliferation
regulation of DNA biosynthetic process
regulation of nucleotide-excision repair
biological_process
proteasome-mediated ubiquitin-dependent protein catabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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