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Invitrogen
SH3GL2 Polyclonal Antibody, Biotin
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FIGURE: 1 / 1
SH3GL2 Antibody (PA5-142943) in WB
Western Blot analysis of SH3GL2 in Human Frontal Cortex lysate (35 µg protein in RIPA buffer) using SH3GL2 Polyclonal Antibody, Biotin (Product # PA5-142943) at 0.3 µg/mL incubated for 1 hour. Detected by chemiluminescence, using streptavidin-HRP and using NAP blocker as a substitute for skimmed milk.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-142943
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence CSLEFPTGDSTQPN.
Conjugate
Biotin
Biotin
Biotin
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
Target Information
Enables identical protein binding activity. Involved in negative regulation of blood-brain barrier permeability; negative regulation of gene expression; and negative regulation of protein phosphorylation. Located in perinuclear region of cytoplasm.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bA335L15.1; bA335L15.1 (SH3-domain GRB2-like 2); contains SH3 domain; endophilin; Endophilin A1 BAR domain; endophilin-1; FLJ20276; FLJ25015; SH3 domain protein 2A; SH3 domain-containing GRB2-like protein 2; SH3-domain GRB2-like 2; SH3GL2; unnamed protein product
Gene Aliases: CNSA2; EEN-B1; SH3D2A; SH3P4
UniProt ID: (Human) Q99962
Entrez Gene ID: (Human) 6456
signal transduction
central nervous system development
negative regulation of gene expression
neuron projection development
negative regulation of epidermal growth factor receptor signaling pathway
negative regulation of MAPK cascade
synaptic vesicle endocytosis
dendrite extension
membrane tubulation
postsynaptic actin cytoskeleton organization
negative regulation of blood-brain barrier permeability
cellular response to brain-derived neurotrophic factor stimulus
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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