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Invitrogen
ACTR1A Polyclonal Antibody
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FIGURE: 1 / 2
ACTR1A Antibody (PA5-18273) in WB
Western blot analysis of ACTR1A using ACTR1A Polyclonal Antibody (Product # PA5-18273) (1 µg/mL) in staining of A431 (A) and HeLa (B), (2 µg/mL) HEK293 (C) and (0.1 µg/mL) MCF7 (D), NIH3T3 (E), KNRK (F) and MDCK (G) cell lysate (35 µg protein in RIPA buffer). Detected by chemiluminescence.
Product Details
PA5-18273
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Mouse,
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (YEEDGARSIHRKT) corresponding to the C-terminus amino acids of ACTR1A (aa 363-376).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with canine, mouse and porcine based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: actin-related protein 1 alpha; actin-related protein 1 homolog A; Actin-RPV; actr1a {ECO:0000250|UniProtKB:P61163}; Alpha-centractin; ARP1; ARP1 actin related protein 1 homolog A; ARP1 actin-related protein 1 homolog A, centractin alpha; Arp1 centractin alpha; Arp1 contractin alpha; Centractin; Centrosome-associated actin homolog; epididymis secretory sperm binding protein; FLJ52695; FLJ52800; FLJ55002; unnamed protein product; yeast homolog A
Gene Aliases: ACTR1A; alpha-Arp1; ARP1; Arp1A; CTRN1
UniProt ID: (Human) P61163, (Dog) P61162, (Mouse) P61164, (Rat) P85515
Entrez Gene ID: (Human) 10121, (Dog) 403791, (Mouse) 54130, (Rat) 294010
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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