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Invitrogen
IDE Polyclonal Antibody
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Product Details
PA5-18753
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (QQYNFDRDNTE) corresponding to the internal amino acids of IDE (aa 914-925).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with canine based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
This gene may belong to a protease family responsible for intercellular peptide signalling. Though its role in the cellular processing of insulin has not yet been defined, insulin-degrading enzyme is thought to be involved in the termination of the insulin response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Abeta-degrading protease; FLJ35968; Insulin degrading enzyme; Insulin protease; Insulin-degrading enzyme; Insulinase; Insulysin; unnamed protein product
Gene Aliases: IDE; INSULYSIN
UniProt ID: (Human) P14735
Entrez Gene ID: (Human) 3416
nucleotide binding
beta-amyloid binding
virus receptor activity
catalytic activity
endopeptidase activity
metalloendopeptidase activity
protein binding
ATP binding
peptidase activity
metallopeptidase activity
zinc ion binding
hydrolase activity
ATPase activity
peptide hormone binding
beta-endorphin binding
peptide binding
identical protein binding
protein homodimerization activity
insulin binding
macromolecular complex binding
metal ion binding
proteolysis
insulin receptor signaling pathway
bradykinin catabolic process
ubiquitin homeostasis
antigen processing and presentation of endogenous peptide antigen via MHC class I
protein catabolic process
positive regulation of protein binding
hormone catabolic process
peptide catabolic process
positive regulation of protein catabolic process
negative regulation of proteolysis
viral entry into host cell
beta-amyloid metabolic process
proteolysis involved in cellular protein catabolic process
beta-amyloid clearance
amyloid-beta clearance by cellular catabolic process
insulin metabolic process
insulin catabolic process
regulation of aerobic respiration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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