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CK2 alpha-1 Polyclonal Antibody
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FIGURE: 1 / 10
CK2 alpha-1 Antibody (PA5-28686) in ICC/IF
CK2 alpha-1 Polyclonal Antibody detects CSNK2A1 protein at cytoplasm and nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: CSNK2A1 protein stained by CK2 alpha-1 Polyclonal Antibody (Product # PA5-28686) diluted at 1:500. Blue: Hoechst 33342 staining.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-28686
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Casein Kinase 2 alpha. The exact sequence is proprietary.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.62 mg/mL
Amount
62 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji, mouse brain, PC-12, Rat2, rat brain.
Predicted reactivity: Mouse (98%), Rat (97%), Zebrafish (84%), Xenopus laevis (86%), Rabbit (100%), Chicken (97%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CSNK2A1 is a serine/threonine protein kinase that phosphorylates acidic proteins. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by CK2 alpha-1 represents the alpha subunit. While CK2 alpha-1 is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for CK2 alpha-1.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: casein kinase 2 alpha; casein kinase 2, alpha 1 polypeptide; casein kinase II alpha 1 polypeptide pseudogene; casein kinase II alpha 1 subunit; casein kinase II, alpha 1 polypeptide; casein kinase II, alpha 1 related sequence 4; CK II alpha; CK2 catalytic subunit alpha; protein kinase CK2; protein kinase; CK2 alpha''; unnamed protein product
Gene Aliases: CK II alpha; CK2; CK2A1; Cka1; Cka2; CKII; Csnk2a1-rs4; OCNDS
UniProt ID: (Human) P68400, (Rat) P19139, (Mouse) Q60737
Entrez Gene ID: (Human) 1457, (Rat) 116549, (Mouse) 12995
double-strand break repair
protein phosphorylation
cellular response to DNA damage stimulus
positive regulation of cell proliferation
negative regulation of translation
peptidyl-serine phosphorylation
cerebral cortex development
positive regulation of Wnt signaling pathway
positive regulation of cell growth
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
response to testosterone
positive regulation of protein catabolic process
protein autophosphorylation
protein stabilization
regulation of cell cycle
symbiont-mediated disruption of host cell PML body
liver regeneration
negative regulation of signal transduction by p53 class mediator
regulation of protein localization to plasma membrane
positive regulation of aggrephagy
regulation of chromosome separation
negative regulation of double-strand break repair via homologous recombination
negative regulation of apoptotic signaling pathway
protein folding
signal transduction
heterochromatin assembly
regulation of protein catabolic process
positive regulation of transcription, DNA-templated
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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