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Invitrogen
TRA2B Polyclonal Antibody
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FIGURE: 1 / 7
TRA2B Antibody (PA5-30170) in IHC (P)
SFRS10 Polyclonal Antibody detects TRA2B protein at nucleus on rat fore brain by immunohistochemical analysis. Sample: Paraffin-embedded rat fore brain. SFRS10 Polyclonal Antibody (Product # PA5-30170) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-30170
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human TRA2B. The exact sequence is proprietary.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.41 mg/mL
Amount
41 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: JurKat.
Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (84%), Xenopus laevis (95%), Pig (100%), Chicken (99%), Sheep (99%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
SFRS10 (also known as TRA2B) is a serine/arginine-rich splicing factor that regulates alternative pre-mRNA splicing by binding to specific RNA sequences. It plays important roles in gene expression, development, and cell differentiation, and can influence processes such as metabolism and disease-related splicing patterns.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alternative splice variant of human splicing factor htra2-beta-1; protein phosphatase 1, regulatory subunit 156; RA301; serine/arginine-rich splicing factor 10; silica-induced gene 41 protein; splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila); TRA-2 beta; TRA2-beta; TRA2B; transformer 2 beta homolog; transformer-2 protein homolog B; unnamed protein product
Gene Aliases: 5730405G21Rik; D16Ertd266e; Htra2-beta; PPP1R156; RAMELN; SFRS10; SIG-41; Silg41; SRFS10; Srsf10; TRA2-BETA; TRA2beta; TRAN2B
UniProt ID: (Human) P62995, (Mouse) P62996, (Rat) P62997
Entrez Gene ID: (Human) 6434, (Mouse) 20462, (Rat) 117259
regulation of alternative mRNA splicing, via spliceosome
mRNA splicing, via spliceosome
cerebral cortex regionalization
regulation of RNA splicing
positive regulation of mRNA splicing, via spliceosome
cellular response to glucose stimulus
embryonic brain development
response to reactive oxygen species
RNA splicing, via transesterification reactions
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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