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Invitrogen
Phospho-STAT2 (Tyr689) Polyclonal Antibody, FITC
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FIGURE: 1 / 1
Phospho-STAT2 (Tyr689) Antibody (PA5-46888) in Flow
Flow cytometry of Phospho-STAT2 (Tyr689) in Daudi human Burkitts lymphoma cell line untreated (light orange filled histogram) or treated with Recombinant Human IFN‚αA (dark orange filled histogram). Samples were incubated in Phospho-STAT2 (Tyr689) polyclonal antibody (Product # PA5-46888) or isotype control. To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer and perme... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-46888
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Phosphopeptide containing the human STAT2 Y689 site
Conjugate
FITC
FITC
FITC
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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