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Invitrogen
LILRA5 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-71394
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthetic peptide directed towards the middle region of human LILRA5
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Leukocyte immunoglobulin-like receptor A5 (LILRA5) is a gene located on chromosome 19q13.42, encoding a protein that is part of the leukocyte immunoglobulin-like receptor (LILR) family. These receptors are primarily expressed on immune cells, such as natural killer cells, monocytes, and dendritic cells, and play a pivotal role in modulating immune responses. LILRA5 is thought to function as an activating receptor, influencing the activation and regulation of immune cell functions. It is implicated in processes such as antigen presentation, cytokine production, and phagocytosis, contributing to both innate and adaptive immune responses. Dysregulation of LILRA5 expression or function can impact immune homeostasis and has been associated with various autoimmune and inflammatory diseases. Research into LILRA5 aims to uncover its specific ligands and signaling pathways, with potential implications for therapeutic targeting in immune-related disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD85 antigen-like family member F; CD85f antigen; immunoglobulin superfamily; immunoglobulin superfamily receptor; immunoglobulin-like transcript 11 protein; leucocyte Ig-like receptor A5; leukocyte Ig-like receptor 9; leukocyte immunoglobulin-like receptor 9; leukocyte immunoglobulin-like receptor subfamily A member 5 soluble; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 7; LIR-family activating receptor 9m1; LIR-family activating receptor 9m2; LIR-family secreted receptor 9s1; LIR-family secreted receptor 9s2
Gene Aliases: CD85; CD85F; ILT-11; ILT11; LILRB7; LIR-9; LIR9
UniProt ID: (Human) A6NI73
Entrez Gene ID: (Human) 353514
immune response-inhibiting cell surface receptor signaling pathway
cytokine-mediated signaling pathway
negative regulation of interleukin-12 production
negative regulation of interleukin-13 production
positive regulation of interleukin-1 beta production
positive regulation of interleukin-10 production
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
positive regulation of MAPK cascade
positive regulation of inflammatory response
positive regulation of cell activation
positive regulation of calcium ion transport
positive regulation of protein tyrosine kinase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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