Invitrogen™

QuantiGene™ Plex Human PanCancer Panel, 80-plex

Catalog number: QGP-180-HUPANCANCER
Invitrogen™

QuantiGene™ Plex Human PanCancer Panel, 80-plex

Catalog number: QGP-180-HUPANCANCER
Catalog Number
QGP-180-HUPANCANCER
Unit Size
1 plate
Price (USD)
Quantity
Catalog Number
Unit Size
3 plates
Price (USD)
Quantity
-
Catalog Number
Unit Size
10 plates
Price (USD)
Quantity
-
Catalog NumberUnit SizePrice (USD)Quantity
QGP-180-HUPANCANCER1 plate
QGP-280-HUPANCANCER3 platesRequest A Quote-
QGP-380-HUPANCANCER10 platesRequest A Quote-
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The QuantiGene Plex Human PanCancer Panel, 80-plex, enables the study and measurement of biomarkers in cancer research by analyzing 80 RNA targets in a single well using Luminex xMAP technology in combination with branched DNA signal amplification. Analyze 80 targets implicated in stages of oncogenesis and potential therapy, including immuno-oncology, angiogenesis, cell proliferation, evasion of growth suppressors, resisting cell death, apoptosis, and angiogenesis.

QuantiGene Plex panels are extensively tested for target combinability, interference, and cross-reactivity to provide the highest level of validation and precision. This kit is not compatible with the MAGPIX instrument.

This panel is used in combination with the QuantiGene Plex Assay Kit, which contains all buffers, plates, and detection reagents necessary to perform the assay in 96-well plates. For detailed information, see QuantiGene Plex Gene Expression Assay Ordering.

Features of the QuantiGene Plex Human PanCancer Panel, 80-plex, include:
True multiplexing—measure 80 genes of interest and housekeeping genes in the same well with no cross-reactivity
Accommodation of difficult sample types—works with degraded and cross-linked RNA in FFPE tissues and blood
Standardized platform—uses 96-well plate format compatible with Luminex 200, FLEXMAP 3D, and INTELLIFLEX systems (384-well format available on demand)
Easy workflow—employs an ELISA-like workflow with direct hybridization of transcripts to beads and transcript labeling (branched DNA signal amplification and PE readout)
Customize with validated targets—if alternative targets are needed in this panel, select from our large inventory of over 22,000 genes to create custom research panels
Rapid turnaround for this catalog panel for fast delivery

Targets: AGER, ARG1, AXL, BDNF, BTLA, CALR, CD27, CD274, CD276, CD28, CD36, CD47, CD48, CD80, CD96, CDH1, CSF3, CTLA4, CXCL8, DKK1, EGF, EPCAM, FGF2, GAPDH, GAS6, GPC1, GUSB, HAVCR2, HGF, HMGB1, HPRT1, HSP90AA1, HSPA4, HSPB2, HSPD1, ICOSLG, IDO1, IGF2, KITLG, LAG3, LGALS9, LIF, MBL2, MDK, MERTK, MICA, MICB, NCR3LG1, NECTIN2, NGF, NT5E, NTRK2, OLR1, PDCD1LG2, PECAM1, PGF, PLAUR, PPIB, PRF1, PVR, RAET1E, S100A8, S100A9, SERPINE1, SIGLEC7, SIGLEC9, SPARC, SPATA2, TIMD4, TNFRSF14, TNFRSF18, TNFRSF4, TNFRSF9, TRIM8, TYRO3, ULBP1, ULBP3, VEGFA, VEGFD, VSIR

Panel and signal amplification technology
QuantiGene Plex assays are hybridization-based assays for the direct quantitation of RNA from cell lysates, tissue homogenates, or purified RNA. They enable the measurement of multiple targets in the same well via multiplexing.

QuantiGene Plex panels contain two components: a target-specific probe set and magnetic capture beads. The target-specific probes are used to capture the RNA of interest, and branched DNA technology then amplifies the fluorescent signals, which are read with a Luminex xMAP instrument. The fluorescent signal is directly proportional to the amount of target mRNA present in the sample. This allows for (relative) quantification of gene expression and with this specific panel enables human immune profiling. Detailed and step-by-step data analysis is facilitated by the QuantiGene Plex data analysis app.

Applications
QuantiGene Plex assay research applications include compound screening of drug candidates, biomarker verification, siRNA knockdown efficiency, prospective and/or retrospective analysis of clinical samples, microarray validation, predictive toxicology, and detection of translocations and fusion genes. In general, any multiplex gene expression analysis can be done with QuantiGene Plex assays, independent of species or sample type.

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Format
96-well
For Use With (Application)
QuantiGene Gene Expression Assay
For Use With (Equipment)
Luminex Instrument
Product Line
QuantiGene™ Plex
Product Type
Multiplex Panel
Quantity
1 Plate
Shipping Condition
Wet Ice
Species
Human
Sample Type
Purified RNA, cell/blood/FFPE lysates, tissue homogenates
Detection Method
Fluorescence

Contents & Storage

Target-specific Probe Set and magnetic Capture Beads (premixed and ready to use).

Store Probe Set at –20°C and Capture Beads at 4°C (do not freeze).

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