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OriGene
SSB Monoclonal Antibody (OTI6G7), TrueMAB™
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Product Details
TA500427
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI6G7
Immunogen
Full-length protein expressed in 293T cell transfected with human SSB expression vector
Conjugate
Form
Liquid
Concentration
1.06 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and systemic lupus erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: autoantigen La; La autoantigen; La ribonucleoprotein; La ribonucleoprotein domain family, member 3; lupus La antigen; Lupus La protein; OTTHUMP00000204777; ribonucleoprotein La; Sjoegren syndrome type B antigen; Sjogren syndrome antigen B; SS-B; SS-B/La protein; unnamed protein product
Gene Aliases: La; La/SSB; LARP3; SSB
UniProt ID: (Human) P05455
Entrez Gene ID: (Dog) 478787, (Human) 6741
tRNA 5'-leader removal
RNA processing
tRNA modification
tRNA export from nucleus
tRNA processing
histone mRNA metabolic process
tRNA 3'-end processing
positive regulation of translation
nuclear histone mRNA catabolic process
IRES-dependent viral translational initiation
protein localization to cytoplasmic stress granule
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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