5'-O-(4,4'-Dimethoxytrityl)thymidine, 98+%

Name: 5'-O-(4,4'-Dimethoxytrityl)thymidine, 98+%
SKU: 044815.02

CAS: 40615-39-2 | C31H32N2O7 | 544.60 g/mol

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Catalog number 044815.02

also known as 044815-02

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Chemical Identifiers

CAS40615-39-2

IUPAC Name1-[(2R,4S,5R)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-4-hydroxyoxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

Molecular FormulaC31H32N2O7

InChI KeyUBTJZUKVKGZHAD-QZGLRKMJNA-N

SMILESCOC1=CC=C(C=C1)C(OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(C)C(=O)NC1=O)(C1=CC=CC=C1)C1=CC=C(OC)C=C1

Specifications

Specification Sheet

Appearance (Color)White to pale cream

FormPowder or crystalline powder or crystals

Assay from Suppliers CofA≥98.0% (HPLC)

Water Content (Karl Fischer Titration)≤1.5%

Residual solvents≤5.0%

5'-O-(4,4'-Dimethoxytrityl)thymidine is used in the solid-phase synthesis of polynucleotides and polythymidylic acids by the block coupling phosphotriester method. Further, it is used in the stereoselective synthesis of 3'-deoxy-3'-threo-hydroxymethyl nucleoside. In addition to this, it is used as a research tool for antiviral and anticancer studies.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

RUO – Research Use Only