It is mainly produced as a precursor to aluminum trifluoride and synthetic cryolite. It is commonly used as a source of fluoride for water fluoridation. Hexafluorosilicic acid is also converted to a variety of useful hexafluorosilicate salts. The potassium salt is used in the production of porcelains, the magnesium salt.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.