Search
Citations & References (13)
Gibco™
Geneticin™ Selective Antibiotic (G418 Sulfate), Powder
Produced by bacterium Micromonospora rhodorangea and acts by binding the ribosome, thus inhibiting protein synthesis in both prokaryotic and eukaryotic cells
Change view
| Catalog Number | Quantity |
|---|---|
| 11811098 | 25 g |
| 11811023 | 1 g |
| 11811031 | 5 g |
Catalog number 11811098
Price (JPY)Contact Us ›
179,700
Online offer
Ends: 27-Mar-2026
299,600Save 119,900 (40%)
Each
Quantity:
25 g
Geneticin™ Selective Antibiotic (G418 Sulfate) is produced by the bacterium Micromonospora rhodorangea and acts by binding the ribosome, thus inhibiting protein synthesis in both prokaryotic and eukaryotic cells. Resistance to Geneticin™ Selective Antibiotic (G418 Sulfate) is conferred by the E. coli APH (3') – I and APH (3') – II resistance genes. Gibco™ Geneticin™ Selective Antibiotic (G418 Sulfate) is used as a selective antibiotic in the concentration range of 100 - 200 μg/mL for bacteria, or 200 – 500 μg/mL for most mammalian cells. This product is supplied as a powder and should be made into a stock solution of 10 – 50 mg/mL in water. We offer a variety of cell culture antibiotics for your convenience.
Product Use
For Research Use Only: Not intended for animal or human diagnostic or therapeutic use.
Dual site cGMP Manufacturing and Quality System
For supply chain continuity, we manufacture Gibco™ Geneticin™ Selective Antibiotic (G418 Sulfate) at two separate facilities located in Grand Island, NY and Scotland, UK. Both sites are compliant with cGMP manufacturing requirements, are certified to ISO 13485, and are registered with the FDA as medical device manufacturers.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Cell TypeEukaryotic Cells, Prokaryotic Cells
Concentration10 to 50 μg/mL
Culture TypeMammalian Cell Culture, Insect Cell Culture
For Use With (Application)Eukaryotic Selection/Stable Cell Line Generation
Product LineGeneticin
Quantity25 g
Shelf Life24 Months
Shipping ConditionRoom Temperature
FormPowder
Product TypeAntibiotic
SterilitySterile
Unit SizeEach
Contents & Storage
Storage conditions: 15 to 30°C
Shipping conditions: Ambient
Shelf life: 24 months from date of manufacture
Shipping conditions: Ambient
Shelf life: 24 months from date of manufacture
Citations & References (13)
Citations & References
Abstract
Cloning and functional expression of a thyrotropin receptor cDNA from rat fat cells.
Journal:J Biol Chem
PubMed ID:7738021
Thyrotropin receptor (TSH-R) has been thought to be thyroid-specific, but, by Northern blot analysis, we found that rat adipose tissue expressed TSH-R mRNAs in amounts approaching those in the thyroid. To investigate the function of TSH-R from adipose tissue, we screened a rat fat cell lambda gt11 cDNA library for
Residues throughout the cytoplasmic domain affect the internalization efficiency of P-selectin.
Journal:J Biol Chem
PubMed ID:7592923
'The cytoplasmic domains of many membrane proteins have short sequences, usually including a tyrosine or a di-leucine, that function as sorting signals. P-selectin is an adhesion receptor for leukocytes that is expressed on activated platelets and endothelial cells. Its 35-residue cytoplasmic domain contains signals for sorting into regulated secretory granules,
Structural basis of G protein specificity of human endothelin receptors. A study with endothelinA/B chimeras.
Journal:J Biol Chem
PubMed ID:7730310
'The endothelin (ET) family of peptides acts via two subtypes of guanine nucleotide-binding regulatory protein (G protein)-coupled receptors termed ETA and ETB. ET-1 stimulated cAMP formation in Chinese hamster ovary (CHO) cells stably expressing human wild-type ETA (CHO/hETA cells) while it inhibited cAMP formation in CHO cells expressing human wild-type
A region of human CD14 required for lipopolysaccharide binding.
Journal:J Biol Chem
PubMed ID:7529231
'CD14, a glycosylphosphatidylinositol-anchored protein on the surface of monocytes, macrophages, and polymorphonuclear leukocytes, is a receptor for lipopolysaccharide (LPS). CD14 binding of LPS is enhanced by serum proteins, especially lipopolysaccharide binding protein. The serum-dependent binding of LPS to CD14 stimulates macrophages to make cytokines, which can cause septic shock in
Mechanisms of desensitization and resensitization of proteinase-activated receptor-2.
Journal:J Biol Chem
PubMed ID:8703006
'Proteinase-activated receptor-2 (PAR-2) is a G-protein-coupled receptor that is expressed by intestinal epithelial cells, which are episodically exposed to pancreatic trypsin in the intestinal lumen. Trypsin cleaves PAR-2 to expose a tethered ligand, which irreversibly activates the receptor. Thus, PAR-2 may desensitize and resensitize by novel mechanisms. We examined these