(-)-Erythromycin, 98%

Erythromycin (E-Mycin or erythrocin), CAS # 114-07-8, is a broad-spectrum antibiotic.

Catalog Number	Quantity	Packaging
227330250	25 g	Plastic Bottle

Catalog number 227330250

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Chemical Identifiers

CAS114-07-8

IUPAC Name(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione

Molecular FormulaC37H67NO13

InChI KeyULGZDMOVFRHVEP-RWJQBGPGSA-N

SMILESCC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O

Specifications

Specific optical rotation-71° to -78° (20°C, 589 nm) (c=2, C2H5OH, 30 minutes) on dry substance

Appearance (Color)White to light yellow

Infrared spectrumConforms

Water=<6.5 % (K.F.)

Appearance (Form)Powder

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Erythromycin is a macrolide antibiotic that works by binding the 50S ribosomal subunit and inhibiting polypeptide formation

• Erythromycin was isolated from Saccharopolyspora erythraea

Applications

• Erythromycin can be used to disrupt the growth of gram-positive and gram-negative bacteria

• Erythromycin has been shown to have motor effects in the gastrointestinal system and can be used for laboratory research on migrating motor complex activity

RUO – Research Use Only

General References:

Dreno, B.; Martin, R.; Moyal, D.; Henley, J.B.; Khammari, A.; Seité, S. Skin microbiome and acne vulgaris: Staphylococcus, a new actor in acne. Exp Dermatol. 2017, 26(9), 798-803.
Wu, F.; Tokach, M.D.; DeRouchey, J.M.; Dritz, S.S.; Woodworth, J.C.; Goodband, R.D.; Chitakasempornkul, K.; Bello, N.M.; Capps, K.; Remfry, S.; Scott, H.M.; Nagaraja, T.G.; Apley, M.D.; Amachawadi, R.G. Effects of Tylosin Administration Routes on the Prevalence of Antimicrobial Resistance Among Fecal Enterococci of Finishing Swine. Foodborne Pathog Dis. 2019, 16(5), 309-316.