alpha-Apo-oxytetracycline, 'can be used as secondary standard'

Alpha-Apo-oxytetracycline, CAS # 18695-01-7, is considered a metabolite formed from oxytetracycline, a member of the tetracycline family, and displays antibiotic activity.

Catalog Number	Quantity	Packaging
257721000	100mg	Glass bottle

Catalog number 257721000

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100mg

Packaging:

Glass bottle

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Chemical Identifiers

CAS18695-01-7

IUPAC Name4-{4,5-dihydroxy-9-methyl-3-oxo-1H,3H-naphtho[2,3-c]furan-1-yl}-3-(dimethylamino)-2,5-dihydroxy-6-oxocyclohex-1-ene-1-carboxamide

Molecular FormulaC22H22N2O8

InChI KeyDRKMHDAKULCOKQ-UHFFFAOYNA-N

SMILESCN(C)C1C(C2OC(=O)C3=C2C(C)=C2C=CC=C(O)C2=C3O)C(O)C(=O)C(C(N)=O)=C1O

Specifications

Infrared spectrumConforms

Appearance (Color)Khaki

Purity>=80 % (as is, calculated)

Appearance (Form)Crystalline powder

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Information
• Alpha-Apo-oxytetracycline is a degradation product of oxytetracycline. When this degradation occurs, two isomers are generated, β- and α -apo-oxytetracycline

Applications
• Alpha-Apo-oxytetracycline compound presents antibiotic activity
• It promotes the inhibition of the growth of aerobic sludge bacteria, Pseudomonas, Agrobacterium, Moraxella, Bacillus, as well as tetracycline-resistant strains of E. coli

RUO – Research Use Only

Literature References

Nguyen, V.; Nguyen, V.; Li, C.; Zhou, G. The degradation of oxytetracycline during thermal treatments of chicken and pig meat and the toxic effects of degradation products of oxytetracycline on rats. Journal of Food Science and Technology. 2015, 52, 2842–2850.

Halling-Sørensen, B.; Sengeløv, G.; Tjørnelund, J. Toxicity of tetracyclines and tetracycline degradation products to environmentally relevant bacteria, including selected tetracycline-resistant bacteria. Archives of Environmental Contamination and Toxicology. 2002, 42, 263–271.