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Thermo Scientific Chemicals
(-)-Erythromycin, Eur.Ph.
Erythromycin (E-Mycin or erythrocin), CAS # 114-07-8, is a broad-spectrum antibiotic.
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| Catalog Number | Quantity | Packaging |
|---|---|---|
| 343880250 | 25 g | Glass Bottle |
| 343880050 | 5 g | Glass Bottle |
Chemical Identifiers
CAS114-07-8
IUPAC Name(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
Molecular FormulaC37H67NO13
InChI KeyULGZDMOVFRHVEP-RWJQBGPGSA-N
SMILESCC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O
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Specifications
Specification Sheet
Specification SheetThiocyanate (SCN)=<0.3 %
HPLC93.0 to 102.0 % (on anhydrous substance)
Water=<6.5 % (K.F.)
Specific optical rotation-71° to -78° (20°C, 589 nm) (c=2, C2H5OH)
Related substances=<7.0 % (HPLC) total impurities
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This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Erythromycin is a macrolide antibiotic that works by binding the 50S ribosomal subunit and inhibiting polypeptide formation
• Erythromycin was isolated from Saccharopolyspora erythraea
Applications
• Erythromycin can be used to disrupt the growth of gram-positive and gram-negative bacteria
• Erythromycin has been shown to have motor effects in the gastrointestinal system and can be used for laboratory research on migrating motor complex activity
RUO – Research Use Only
Literature References
Dreno, B.; Martin, R.; Moyal, D.; Henley, J.B.; Khammari, A.; Seité, S. Skin microbiome and acne vulgaris: Staphylococcus, a new actor in acne. Exp Dermatol. 2017, 26(9), 798-803.
Wu, F.; Tokach, M.D.; DeRouchey, J.M.; Dritz, S.S.; Woodworth, J.C.; Goodband, R.D.; Chitakasempornkul, K.; Bello, N.M.; Capps, K.; Remfry, S.; Scott, H.M.; Nagaraja, T.G.; Apley, M.D.; Amachawadi, R.G. Effects of Tylosin Administration Routes on the Prevalence of Antimicrobial Resistance Among Fecal Enterococci of Finishing Swine. Foodborne Pathog Dis. 2019, 16(5), 309-316.