Chlortetracycline hydrochloride, specified according to the requirements of Ph.Eur.

Name: Chlortetracycline hydrochloride, specified according to the requirements of Ph.Eur.
SKU: 430960050

Chlortetracycline hydrochloride, CAS # 64-72-2, is a broad-spectrum antibiotic of the tetracycline family. | CAS: 64-72-2 | C₂₂H₂₃ClN₂O₈·HCl | 515.33 g/mol

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5 g

100 g

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Glass bottle

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Catalog number 430960050

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5 g

Packaging:

Glass bottle

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Chemical Identifiers

CAS64-72-2

IUPAC Namehydrogen (2Z,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylidene]-7-chloro-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-1,2,3,4,4a,5,5a,6,12,12a-decahydrotetracene-1,3,12-trione chloride

Molecular FormulaC22H24Cl2N2O8

InChI KeyRRXOSDMYCQSQHB-MRYPCDLHSA-N

SMILES[H+].[Cl-].CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)C4=C(O)C=CC(Cl)=C4[C@@]3(C)O)C(=O)[C@]2(O)C(=O)C(=C(N)O)C1=O

Specifications

Specification Sheet

Appearance (Color)Yellow

Assay>=89.5 % Chlortetracycline hydrochloride,

Specific optical rotationOn dry substance

Water=<2.0 %

IdentificationPasses test

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General features
• Chlortetracycline hydrochloride is a broad-spectrum antibiotic of the tetracycline family
• Receives its name from a 7-chloro substitution on one of the rings of its parent structure, tetracycline
• A bacteriostatic that inhibits the 30S ribosomal subunit and prevents peptide formation
• Can work as an antiprotozoal and antifungal

Applications
• Chlortetracycline is suitable for use in biochemistry, microbiology, in vivo research, and cell culture
• Intended for research use only

RUO – Research Use Only

General References:

Chen, C.; Ray, P.; Knowlton, K.F.; Pruden, A.; Xia, K. Effect of composting and soil type on dissipation of veterinary antibiotics in land-applied manures. Chemosphere. 2018, 196:270-279.
Weinroth, M.D.; Scott, H.M.; Norby, B.; Loneragan, G.H.; Noyes, N.R.; Rovira, P.; Doster, E.; Yang, X.; Woerner, D.R.; Morley, P.S.; Belk, K.E. Effects of Ceftiofur and Chlortetracycline on the Resistomes of Feedlot Cattle. Appl Environ Microbiol. 2018, 84(13), e00610-18.