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Thermo Scientific Chemicals
Carbenicillin disodium salt, 90%
Carbenicillin disodium salt, CAS # 4800-94-6, is the disodium salt form of carbenicillin, a semisynthetic compound with broad-spectrum antibacterial and β-lactamase-resistant activities.
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| Catalog Number | Quantity |
|---|---|
| 455360050 | 5 g |
| 455360010 | 1 g |
Chemical Identifiers
CAS4800-94-6
IUPAC Namedisodium (2S,5R,6R)-6-(2-carboxylato-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Molecular FormulaC17H16N2Na2O6S
InChI KeyRTYJTGSCYUUYAL-YCAHSCEMSA-L
SMILES[Na+].[Na+].CC1(C)S[C@@H]2[C@H](NC(=O)C(C([O-])=O)C3=CC=CC=C3)C(=O)N2[C@H]1C([O-])=O
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Specifications
Specification Sheet
Specification SheetAppearance (Color)White to light yellow
Appearance (Form)Powder or crystalline powder
Water=<6.0 %
HPLC>=88 %
Solubility(5 % in water) Clear to light yellow
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Carbenicillin disodium salt is a semisynthetic compound with antibacterial and β-lactamase-resistant activities and is effective against gram-negative bacteria
• In in vitro studies, carbenicillin disodium salt can totally suppress the proliferation of Agrobacterium
Application
• Due to its antibacterial activity this compound can be used to control bacterial cell wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane. This can lead to incomplete bacterial cell wall synthesis to eventually cause cell lysis
• It has also been used in studies to evaluate the role of penicillin-sensitive transpeptidases in cell wall biosynthesis
RUO – Research Use Only
Literature References
Cole, M. R.; Hobden, J. A.; Warner, I. M. Recycling Antibiotics into GUMBOS: A New Combination Strategy to Combat Multi-Drug-Resistant Bacteria. Molecules 2015, 20 (4), 6466-6487.
Sonopo, M. S.; Venter, K.; Boyle, G.; Winks, S.; Painter, B. M.; Zeevaart, J. R. Carbon-14 radiolabeling and in vivo biodistribution of a potential anti-TB compound. J. Labelled Comp. Radiopharm. 2015, 58 (2), 23-29.