SMART Digest™ Chymotrypsin Kits
SMART Digest™ Chymotrypsin Kits
Actual product may vary
Thermo Scientific™

SMART Digest™ Chymotrypsin Kits

Obtain fast, simple, and highly reproducible chymotrypsin protein digestion for peptide characterization and quantitation in biopharmaceutical research.

Catalog NumberDescription
60109-105-MBSMART Digest Chymotrypsin Kit, Magnetic Bulk Resin option with Filter/Collection plate
60109-104SMART Digest Chymotrypsin Kit, with Collection plate
60109-104-MB-LPHSMART Digest Low pH Chymotrypsin Kit, Magnetic Beads, Bulk option for MAM workflows
60109-104-BSMART Digest Chymotrypsin Kit, Bulk Resin option
60109-104-MBSMART Digest Chymotrypsin Kit, Magnetic Bulk Resin option
60109-105SMART Digest Chymotrypsin Kit, with Filter/Collection plate
60109-105-BSMART Digest Chymotrypsin Kit, Bulk Resin option with Filter/Collection plate
60109-106SMART Digest Chymotrypsin Kit with SOLAμ/collection plate
60109-106-BSMART Digest Chymotrypsin Kit Bulk Resin option with SOLAμ/collection plate
60109-106-MBSMART Digest Chymotrypsin Kit Magnetic Bulk Resin option with SOLAμ/collection plate
10 Options
Catalog number 60109-105-MB
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Description:
SMART Digest Chymotrypsin Kit, Magnetic Bulk Resin option with Filter/Collection plate

Obtain high-quality analytical results from protein digests using Thermo Scientific™ SMART Digest™ Chymotrypsin Kits. A significant advance in sample preparation for biopharmaceutical protein research, these kits provide fast and simple protein digestion with high reproducibility, high sensitivity, and high levels of data quality in a format that's compatible with automation. SMART Digest Kits are a significant improvement over in-solution protein digestion technologies, which are not reproducible, have poor sensitivity, and employ protracted methodologies not amenable to automation.

Chymotrypsin Protein Digestion

Characterize and quantitate proteins faster, easier, and quicker than ever before using SMART Digest kits. This version of the kit uses chymotrypsin, which cleaves peptide bonds formed by aromatic residues such as tyrosine, phenylalanine, and tryptophan.

Easy and Simple
  • Significantly increased speed of sample processing
  • Simple process
  • Easily automate entire protocol for high-throughput processing
Reliable Results
  • Increased reproducibility over existing protocols
  • Higher sensitivity
  • Higher data confidence
Significantly Reduces Sample Preparation Time

Typically it takes less than 60 minutes (dependent on sample complexity) to achieve full digestion, whereas an in-solution digestion can take up to 24 hours.

Cleaner Samples

Reduction in the number of chemicals used and the immobilized chymotrypsin design helps mitagate against chemically induced post translational modifications (PTMs) and autolysis. The results are easier to interpret.

Couple with SOLAμ SPE plates for desalting

When used with the SMART Digest for desalting, Thermo Scientific™ SOLAμ™ SPE solid phase extraction plates provide a fast, easy-to-use, robust, and easily automatable sample preparation solution for analysis of biomolecules.

Specifications
DescriptionSMART Digest Chymotrypsin Kit, Magnetic Bulk Resin option with Filter/Collection plate
CaptureNone
CleavagePeptide bonds of aromatic residues (e.g., tyrosine, phenylalanine, tryptophan)
EnzymeChymostrypsin
FormatSMART Digest Resin, Bulk Magnetic
For Use With (Application)Peptide Quantitation, Peptide Mapping
Product LineSMART Digest
TypeProtein Digestion
IncludesBulk Magnetic SMART Digest Resin, SMART Digest Buffer, Collection Plate, Filter Plate
Unit SizeEach