(S)-(-)-Nicotine, 98+%

Name: (S)-(-)-Nicotine, 98+%
SKU: A12398.22

L-Nicotine, CAS # 54-11-5, has been shown in laboratory studies to alleviate smoking habits. It is also known as 3-(1-methyl-2-pyrrolidinyl)pyridine or (S)-(-)-nicotine. | CAS: 54-11-5 | C10H14N2 | 162.236 g/mol

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Catalog number A12398.22

also known as A12398-22

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Quantity:

100 g

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Chemical Identifiers

CAS54-11-5

IUPAC Name3-[(2S)-1-methylpyrrolidin-2-yl]pyridine

Molecular FormulaC10H14N2

InChI KeySNICXCGAKADSCV-JTQLQIEISA-N

SMILESCN1CCC[C@H]1C1=CC=CN=C1

Specifications

Specification Sheet

Appearance (Color)Clear colorless to yellow to orange to brown

FormLiquid

Assay (GC)≥98.0%

Identification (FTIR)Conforms

Optical Rotation-160° to -170° (neat) or -140° to -152° (c=2, ethanol)

(S)-(-)-Nicotine is utilized as a therapeutic agent to eliminate smoking with the damage it does to health. It is widely used as a drug to enhance the memory or other cognition functions, which is second to caffeine. Lesser levels of nicotine given in the form of gum, may help to eliminate smoking.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description
• L-Nicotine is a naturally occuring alkaloid in the nightshade family of plants
• It is also known as 3-(1-methyl-2-pyrrolidinyl)pyridine or (S)-(-)-nicotine
Applications
• L-Nicotine has been shown in studies to alleviate smoking habits
• It has also been shown to enhance cognitive functions such as memory
• Studies show that lower levels of nicotine in the form of gum may also help eliminate smoking habits

RUO – Research Use Only

General References:

Ortega, P. G. R.; Montejo, M.; González, J. J. L. Vibrational Circular Dichroism and Theoretical Study of the Conformational Equilibrium in (-)-S-Nicotine. Angew. Chem. 2015, 16 (2), 342-352.
Zhou, T.; Jørgensen, L.; Mattebjerg, M. A.; Chronakis, I. S.; Ye, L. Molecularly imprinted polymer beads for nicotine recognition prepared by RAFT precipitation polymerization: a step forward towards multi-functionalities. RSC Adv. 2014, 4,30292-30299.