Trimethylacetaldehyde, 95%
Trimethylacetaldehyde, 95%
Trimethylacetaldehyde, 95%
Trimethylacetaldehyde, 95%
Thermo Scientific Chemicals

Trimethylacetaldehyde, 95%

CAS: 630-19-3 | C5H10O | 86.13 g/mol
Quantity:
5 g
25 g
100 g
Catalog number A15013.14
also known as A15013-14
Price (JPY)
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25 g
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Chemical Identifiers
CAS630-19-3
SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)Clear colorless
FormLiquid
Assay (GC)≥94.0%
Identification (FTIR)Conforms
Refractive Index1.3760-1.3820 @ 20°C
Trimethylacetaldehyde is used as a stereoselective synthesis application. It is also used as a building block used in aldol condensation reactions. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trimethylacetaldehyde is used as a stereoselective synthesis application. It is also used as a building block used in aldol condensation reactions. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.

Solubility
It is virtually insoluble in water but soluble in chloroform.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away from oxidizing agents, strong reducing agents.
RUO – Research Use Only

General References:

  1. Anna K. Szardenings.; Timothy S. Burkoth.; Gary C. Look.; David A. Campbell. A Reductive Alkylation Procedure Applicable to Both Solution- and Solid-Phase Syntheses of Secondary Amines. J. Org. Chem. 1996, 61, (19), 6720-6722.
  2. Samiran Bhattacharjee.; Kwang-Eun Jeong.; Soon-Yong Jeong.; Wha-Seung Ahnl. Synthesis of a sulfonato-salen-nickel(II) complex immobilized in LDH fortetralin oxidation. New J. Chem. 2010, 34, 156-162.
  3. Derivatizing agent for amino acids, forming oxazolidinones as volatile derivatives for GC: Anal. Biochem., 49, 442 (1972); Aust. J. Biol. Sci., 26, 831 (1973).
  4. For formation of the fused pyrrolidino-oxazolidinone from L-proline, catalyzed by trifluoroacetic acid, and use of the product in a synthesis of ɑ-branched amino acids, see: Org. Synth. Coll., 9, 626 (1998):
  5. For use in the protection of asparagine as a tetrahydropyrimidinone derivative, see: Org. Synth. Coll., 9, 17 (1998). For use of this system in ɑ-alkylation of (S)-asparagine with self-regeneration of the stereogenic center, see: J. Org. Chem., 63, 4706 (1998).
  6. Promotes the epoxidation of alkenes with molecular oxygen: Tetrahedron Lett., 33, 6827 (1992).
  7. The imine formed with ethylamine has been used to convert aryl chlorides to the hindered tertiary amides: N-ethyl-N-(1-methoxy-2,2-dimethylpropyl)benzamides, which can be ortho metallated cleanly at higher temperatures than other amide systems: J. Org. Chem., 60, 8417 (1995).