2,6-Difluorobenzyl chloride, 98%, Thermo Scientific Chemicals

Catalog Number	Quantity
A19472.06 also known as A19472-06	5 g

Catalog number A19472.06

also known as A19472-06

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Chemical Identifiers

CAS697-73-4

IUPAC Name2-(chloromethyl)-1,3-difluorobenzene

Molecular FormulaC7H5ClF2

InChI KeyMJXRENZUAQXZGJ-UHFFFAOYSA-N

SMILESFC1=CC=CC(F)=C1CCl

Specifications

Appearance (Color)White

Assay (GC)≥97.5%

FormFused low-melting solid

2,6-Difluorobenzyl chloride is used as rufinamide intermediate. It is an important raw material and intermediate used in organic synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2,6-Difluorobenzyl chloride is used as rufinamide intermediate. It is an important raw material and intermediate used in organic synthesis.

Solubility
Soluble in acetone, DMSO and DMF. Insoluble in water.

Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

RUO – Research Use Only

General References:

Naresh H. Tarte.; Hyun Yong Cho.; Seong Ihl Woo. Efficient Route for Cyclic Olefin Polymerization: Nonchelated Monodentate Benzimidazole Nickel(II) Complex Catalysts for Vinyl Polymerization of Norbornene. Macromolecules. 2007, 40, (23), 8162-8167.
Eric A. Standley.; Timothy F. Jamison. Simplifying Nickel(0) Catalysis: An Air-Stable Nickel Precatalyst for the Internally Selective Benzylation of Terminal Alkenes. J. Am. Chem. Soc. 2013, 135, (4), 1585-1592.