Aldehyde/Sulfate Latex Beads, 4% w/v, 4 μm
Aldehyde/Sulfate Latex Beads, 4% w/v, 4 μm
Invitrogen™

Aldehyde/Sulfate Latex Beads, 4% w/v, 4 μm

Microspheres (also called latex beads or latex particles) are spherical particles in the colloidal size range that are formed fromRead more
Catalog NumberQuantity
A3730415 mL
Catalog number A37304
Price (JPY)
44,200
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Ends: 27-Mar-2026
73,800
Save 29,600 (40%)
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Quantity:
15 mL
Microspheres (also called latex beads or latex particles) are spherical particles in the colloidal size range that are formed from an amorphous polymer such as polystyrene. Because of the way that the polystyrene chains arrange themselves in the bead, the surface is very hydrophobic in character, making these ideal materials for the adsorption of materials such as proteins.

This aldehyde/sulfate latex contains an abundance of aldehyde groups grafted to the surface of the polymer particle. The high density of aldehyde groups enables facile coupling of proteins and other materials to the latex particles in a one-step process. The sulfate charge groups on the microspheres enable retention of stability during the covalent coupling process. Due to the high density of polar groups, this latex has a hydrophilic surface.

Microspheres Are Available in Many Sizes and Surface Functionalities
25 sizes to choose from—0.02 microns to 16 microns
20 different surface—for ready conjugation to virtually any material
Surfactant free—ultraclean
Various quantities—from milliliter to 500-liter amounts

Key Applications of Microspheres
Instrument calibration (flow cytometry, microscopy, HTS, HCS)
Flow testing (microfluidics, blood flow, water flow, and air flow)
Cell biology tracers (cell differentiation and cell tracing)
Immunoassays (agglutination tests, ELISA, particle capture, and contrast reagents)

Get More Information
Read a technical overview of microspheres and find out about high activity beads, super active beads, specialty beads, and review bead-coupling protocols on the IDC Surfactant-free Latex Beads application page.

We’ll Make a Custom Microsphere Product for You
If you don’t see the microsphere you’re looking for in our stocked list, we’ll make a custom microsphere for you. Our custom conjugation service is efficient and confidential, and we guarantee the quality of our work. We are ISO 13485:2000 certified.

For Research Use Only. Not intended for animal or human therapeutic or diagnostic use.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Product LineIDC
Quantity15 mL
Shipping ConditionRoom Temperature
Surface ModificationAldehyde Sulfate
For Use With (Application)Flow Cytometry
Product TypeLatex Beads
Unit SizeEach
Contents & Storage
Store in refrigerator (2–8°C).

Citations & References (19)

Citations & References
Abstract
Cancer exosomes trigger fibroblast to myofibroblast differentiation.
Authors:Webber J, Steadman R, Mason MD, Tabi Z, Clayton A,
Journal:Cancer Res
PubMed ID:21098712
There is a growing interest in the cell-cell communication roles in cancer mediated by secreted vesicles termed exosomes. In this study, we examined whether exosomes produced by cancer cells could transmit information to normal stromal fibroblasts and trigger a cellular response. We found that some cancer-derived exosomes could trigger elevated ... More
Targeting tumor antigens to secreted membrane vesicles in vivo induces efficient antitumor immune responses.
Authors:Zeelenberg IS, Ostrowski M, Krumeich S, Bobrie A, Jancic C, Boissonnas A, Delcayre A, Le Pecq JB, Combadière B, Amigorena S, Théry C,
Journal:Cancer Res
PubMed ID:18281500
'Expression of non-self antigens by tumors can induce activation of T cells in vivo, although this activation can lead to either immunity or tolerance. CD8+ T-cell activation can be direct (if the tumor expresses MHC class I molecules) or indirect (after the capture and cross-presentation of tumor antigens by dendritic ... More
Plasma exosomes can deliver exogenous short interfering RNA to monocytes and lymphocytes.
Authors:Wahlgren J, De L Karlson T, Brisslert M, Vaziri Sani F, Telemo E, Sunnerhagen P, Valadi H,
Journal:Nucleic Acids Res
PubMed ID:22618874
'Despite the promise of RNA interference (RNAi) and its potential, e.g. for use in cancer therapy, several technical obstacles must first be overcome. The major hurdle of RNAi-based therapeutics is to deliver nucleic acids across the cell''s plasma membrane. This study demonstrates that exosome vesicles derived from humans can deliver ... More
Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis.
Authors:Fitzner D, Schnaars M, van Rossum D, Krishnamoorthy G, Dibaj P, Bakhti M, Regen T, Hanisch UK, Simons M,
Journal:J Cell Sci
PubMed ID:21242314
'The transfer of antigens from oligodendrocytes to immune cells has been implicated in the pathogenesis of autoimmune diseases. Here, we show that oligodendrocytes secrete small membrane vesicles called exosomes, which are specifically and efficiently taken up by microglia both in vitro and in vivo. Internalisation of exosomes occurs by a ... More
Exosomal evasion of humoral immunotherapy in aggressive B-cell lymphoma modulated by ATP-binding cassette transporter A3.
Authors:Aung T, Chapuy B, Vogel D, Wenzel D, Oppermann M, Lahmann M, Weinhage T, Menck K, Hupfeld T, Koch R, Trümper L, Wulf GG,
Journal:Proc Natl Acad Sci U S A
PubMed ID:21873242
'Targeting the surface of malignant cells has evolved into a cornerstone in cancer therapy, paradigmatically introduced by the success of humoral immunotherapy against CD20 in malignant lymphoma. However, tumor cell susceptibility to immunochemotherapy varies, with mostly a fatal outcome in cases of resistant disease. Here, we show that lymphoma exosomes ... More