Pierce™ FlexMix™ Calibration Solution
Pierce™ FlexMix™ Calibration Solution
Thermo Scientific™

Pierce™ FlexMix™ Calibration Solution

The Thermo Scientific Pierce FlexMix Calibration Solution is a mixture of 16 highly pure, ionizable components (mass ranges: 50 toRead more
Catalog NumberQuantity
A3923910 mL
Catalog number A39239
Price (JPY)
68,600
Each
Contact Us ›
Quantity:
10 mL
The Thermo Scientific Pierce FlexMix Calibration Solution is a mixture of 16 highly pure, ionizable components (mass ranges: 50 to 3000 m/z) designed for both positive and negative ionization calibration using Orbitrap Tribrid Series 3.1 Instrument Control Software (or later) for Orbitrap Fusion, Orbitrap Fusion Lumos, and Orbitrap ID-X MS instruments.

Pierce FlexMix Calibration Solution features include:
Improved mass accuracy—extended mass range improves mass accuracy
Positive and negative mode calibration—single formulation with extended mass ranges for both ionization calibration modes
Highly validated—high-quality, rigorously-tested formulation with lot-specific certificates of analysis
Ready-to-use—reference standard may be directly loaded into a syringe and injected into the instrument
Stable—store at room temperature for up to 18 months (see CofA for specific expiration date of each lot)

The Pierce FlexMix Calibration Solution is a ready-to-use formulation that has been optimized for both positive and negative ionization calibration of instruments. The extended range masses (50 to 3000 m/z) improve sensitivity and mass accuracy of Orbitrap mass spectrometers. Additionally, the FlexMix Calibration Solution is manufactured at an ISO 9001 facility and each lot is quality controlled with strict specifications. The stable solution is provided in a leak-proof, high-purity PTFE bottle.

For the calibration procedure, use the Orbitrap Tribrid Series Getting Started Guide.

Related products:
Pierce HeLa Protein Digest Standard
Pierce TMT11plex Yeast Digest Standard

For Research Use Only. Not for use in diagnostic procedures.
Specifications
Chemical ReactivityAmine
For Use With (Equipment)Mass Spectrometer
Quantity10 mL
Shipping ConditionRoom Temperature
Workflow StepCalibration
FormLiquid
Product LinePierce
Product TypeCalibration Solution
Unit SizeEach

Frequently asked questions (FAQs)

What is the difference between Pierce FlexMix Calibration Solution and Pierce FlexMix Calibration Solution for Auto-Ready Mass Spectrometers?

Both the Pierce FlexMix Calibration Solution and Pierce FlexMix Calibration Solution for Auto-Ready Mass Spectrometers have the same 16 components and produce the same spectra. However, the Pierce FlexMix Calibration Solution for Auto-Ready Mass Spectrometers has a different storage solution: LC-MS grade acetonitrilie 87% (v/v) and LC-MS grade water 13% (v/v). The FlexMix Calibration for Auto-Ready Mass Spectrometers is designed to be used only in mass spectrometer instruments with autocalibration feature, such as Orbitrap IQ-X Mass Spectrometer using Orbitrap Tribrid Series 3.5 Instrument Control Software (or later).

Find additional tips, troubleshooting help, and resources within our Mass Spectrometry Support Center.

What type of instruments does the Pierce FlexMix Calibration Solution work with?

We recommend using the Pierce FlexMix Calibration Solution with Orbitrap Fusion, Orbitrap Fusion Lumos, and Orbitrap ID-X MS instruments.

Find additional tips, troubleshooting help, and resources within our Mass Spectrometry Support Center.

What is the Pierce FlexMix Calibration Solution, and what is its main purpose?

The Pierce FlexMix Calibration Solution is a mixture of 16 highly pure, ionizable components (mass ranges: 50 to 3,000 m/z) designed for both positive and negative ionization calibration using Orbitrap Tribrid Series 3.1 Instrument Control Software (or later) for Orbitrap Fusion, Orbitrap Fusion Lumos, and Orbitrap ID-X MS instruments.

Find additional tips, troubleshooting help, and resources within our Mass Spectrometry Support Center.

Citations & References (5)

Citations & References
Abstract
Improved Skin Barrier Function Along with Hydration Benefits of Viola yedoensis Extract, Aesculin, and Schaftoside and LC-HRMS/MS Dereplication of Its Bio-Active Components.
Authors:Thonthula S,Sousa S,Dubuis A,Boudah S,Mehta R,Singh A,Eilstein J,Tabet JC,John S,Roy D,Pannakal ST
Journal:International journal of molecular sciences
PubMed ID:39684479
The skin hydration level is a key factor that influences the physical and mechanical properties of the skin. The stratum corneum (SC), the outermost layer of the epidermis, is responsible for the skin's barrier function. In this study, we investigated the role of a unique composition of Viola yedoensis extract ... More
Pharmacometabolomics via real-time breath analysis captures metabotypes of asthmatic children associated with salbutamol responsiveness
Authors:Zeng J, Usemann J, Singh KD, Jochmann A, Trachsel D, Frey U, Sinues P.
Journal:iScience
PubMed ID:39697593
Asthma is a widespread respiratory disease affecting millions of children. Salbutamol is a well-established bronchodilator available to treat asthma. However, response to bronchodilators is very heterogeneous, particularly in children. Pharmacometabolomics via exhaled breath analysis holds promise for patient stratification. Here, we integrate a real-time breath analysis platform in the workflow ... More
High-throughput identification of gut microbiome-dependent metabolites
Authors:Han S, Guiberson ER, Li Y, Sonnenburg JL.
Journal:Nat Protoc
PubMed ID:38740909
A significant hurdle that has limited progress in microbiome science has been identifying and studying the diverse set of metabolites produced by gut microbes. Gut microbial metabolism produces thousands of difficult-to-identify metabolites, which present a challenge to study their roles in host biology. In recent years, mass spectrometry-based metabolomics has ... More
Multilevel Proteomic Profiling of Colorectal Adenocarcinoma Caco-2 Cell Differentiation to Characterize an Intestinal Epithelial Model.
Authors:Fekete EE,Wang A,Creskey M,Cummings SE,Lavoie JR,Ning Z,Li J,Figeys D,Chen R,Zhang X
Journal:Journal of proteome research
PubMed ID:38810023
Emergent advancements on the role of the intestinal microbiome for human health and disease necessitate well-defined intestinal cellular models to study and rapidly assess host, microbiome, and drug interactions. Differentiated Caco-2 cell line is commonly utilized as an epithelial model for drug permeability studies and has more recently been utilized ... More
A guide to precise measurements of isotope abundance by ESI-Orbitrap MS.
Authors:Kantnerová K,Kuhlbusch N,Juchelka D,Hilkert A,Kopf S,Neubauer C
Journal:Nature protocols
PubMed ID:38654136
Stable isotopes of carbon, hydrogen, nitrogen, oxygen and sulfur are widespread in nature. Nevertheless, their relative abundance is not the same everywhere. This is due to kinetic isotope effects in enzymes and other physical principles such as equilibrium thermodynamics. Variations in isotope ratios offer unique insights into environmental pollution, trophic ... More