(S)-2-Aminomethyl-1-Boc-pyrrolidine, 97%
(S)-2-Aminomethyl-1-Boc-pyrrolidine, 97%
(S)-2-Aminomethyl-1-Boc-pyrrolidine, 97%
Thermo Scientific Chemicals

(S)-2-Aminomethyl-1-Boc-pyrrolidine, 97%

CAS: 119020-01-8 | C10H20N2O2 | 200.28 g/mol
Quantity:
1 g
5 g
Catalog number H52727.03
also known as H52727-03
Price (JPY)
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Quantity:
1 g
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Chemical Identifiers
CAS119020-01-8
IUPAC Nametert-butyl (2S)-2-(aminomethyl)pyrrolidine-1-carboxylate
Molecular FormulaC10H20N2O2
InChI KeySOGXYCNKQQJEED-QMMMGPOBSA-N
SMILESCC(C)(C)OC(=O)N1CCC[C@H]1CN
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SpecificationsSpecification SheetSpecification Sheet
Water Content (Karl Fischer Titration)<0.5%
Assay (unspecified)>96.0%
Loss on Drying<0.10%
(S)-2-Aminomethyl-1-Boc-pyrrolidine acts as an intermediate in organic synthesis. It is also used as a chiral and heterocyclic building block in synthetic chemistry.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(S)-2-Aminomethyl-1-Boc-pyrrolidine acts as an intermediate in organic synthesis. It is also used as a chiral and heterocyclic building block in synthetic chemistry.

Solubility
Miscible with N-methylpyrrolidinone.

Notes
Air and moisture sensitive. Store in a cool place. Incompatible with oxidizing agents, strong acids and bases.
RUO – Research Use Only

General References:

  1. Patwardhan, N. N.; Morris, E. A.; Kharel, Y.; Raje, M. R.; Gao, M.; Tomsig, J. L.; Lynch, K. R.; Santos, W. L. Structure-Activity Relationship Studies and in Vivo Activity of Guanidine-Based Sphingosine Kinase Inhibitors: Discovery of SphK1- and SphK2-Selective Inhibitors. J. Med. Chem. 2015, 58 (4), 1879-1899.
  2. Morris, L. C.; Nance, K. D.; Gentry, P. R.; Days, E. L.; Weaver, C. D.; Niswender, C. M.; Thompson, A. D.; Jones, C. K.; Locuson, C. W.; Morrison, R. D.; Daniels, J. S.; Niswender, K. D.; Lindsley, C. W. Discovery of (S)-2-Cyclopentyl-N-((1-isopropylpyrrolidin2-yl)-9-methyl-1-oxo-2,9-dihydro-1H-pyrrido[3,4-b]indole-4-carboxamide (VU0453379): A Novel, CNS Penetrant Glucagon-Like Peptide 1 Receptor (GLP-1R) Positive Allosteric Modulator (PAM). J. Med. Chem. 2014, 57 (23), 10192-10197.