N-Fmoc-L-alanine, 95%
N-Fmoc-L-alanine, 95%
N-Fmoc-L-alanine, 95%
Thermo Scientific Chemicals

N-Fmoc-L-alanine, 95%

CAS: 35661-39-3 | C18H17NO4 | 311.337 g/mol
Quantity:
5 g
25 g
Catalog number H59438.06
also known as H59438-06
Price (JPY)
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Quantity:
5 g
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Chemical Identifiers
CAS35661-39-3
IUPAC Name2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
Molecular FormulaC18H17NO4
InChI KeyQWXZOFZKSQXPDC-UHFFFAOYNA-N
SMILESCC(NC(=O)OCC1C2=CC=CC=C2C2=CC=CC=C12)C(O)=O
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SpecificationsSpecification SheetSpecification Sheet
Assay (HPLC)94.0% min
N-Fmoc-L-alanine is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Alanine is one of the simplest amino acids - a methyl group as the side chain. This small side chain confers a high degree of flexibility when incorporated into a polypeptide chain. The Fmoc group is typically removed with a base such as pyridine - an orthogonal de-protection strategy to the acid labilie Boc group.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N-Fmoc-L-alanine is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Alanine is one of the simplest amino acids - a methyl group as the side chain. This small side chain confers a high degree of flexibility when incorporated into a polypeptide chain. The Fmoc group is typically removed with a base such as pyridine - an orthogonal de-protection strategy to the acid labilie Boc group.

Solubility
Soluble in water.

Notes
Keep container tightly closed. Store away from oxidizing agents.
RUO – Research Use Only

General References:

  1. Roger M. Freidinger.; Jeffery S. Hinkle.; Debra S. Perlow. Synthesis of 9-fluorenylmethyloxycarbonyl-protected N-alkyl amino acids by reduction of oxazolidinones. J. Org. Chem. 1983, 48, (1), 77-81.
  2. Shu-Li You.; Jeffery W. Kelly. Total synthesis of didmolamides A and B. Tetrahedron Letters. 2005, 46, (15), 2567-2570.