Calciferol
Calciferol
Calciferol
Thermo Scientific Chemicals

Calciferol

CAS: 50-14-6 | C28H44O | 396.66 g/mol
Quantity:
1 g
10 g
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Catalog number J61610.09
also known as J61610-09
Price (JPY)
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Quantity:
10 g
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Chemical Identifiers
CAS50-14-6
IUPAC Name(1S,3E)-3-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexan-1-ol
Molecular FormulaC28H44O
InChI KeyMECHNRXZTMCUDQ-VLOQVYPSSA-N
SMILESCC(C)[C@@H](C)\C=C\[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1/C[C@@H](O)CCC1=C
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SpecificationsSpecification SheetSpecification Sheet
FormPowder or crystals or crystalline powder
Appearance (Color)White
Melting Point114.0-120.0°C
Assay (unspecified)≥97.0%
Optical Rotation+102 to + 107°
Calciferol is a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Calciferol also been shown to be an inhibitor of DNA polymerase.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Calciferol is a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Calciferol also been shown to be an inhibitor of DNA polymerase.

Solubility
Soluble in ethanol, water, methanol, dimethylformamide, and dimethyl sulfoxide.

Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
RUO – Research Use Only

General References:

  1. Gui-Dong. Zhu.; William H. Okamura. Synthesis of Vitamin D (Calciferol). Chem. Rev. 1995, 95, (6), 1877-1952.
  2. Maryka H. Bhattacharyya.; H.F. DeLuca. Subcellular location of rat liver calciferol-25-hydroxylase. Archives of Biochemistry and Biophysics. 1974, 160, (1), 58-62.