Guanosine-5'-diphosphate disodium salt

Name: Guanosine-5'-diphosphate disodium salt
SKU: J61646.ME

CAS: 7415-69-2 | C10H13N5Na2O11P2 | 487.17 g/mol

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Catalog number J61646.ME

also known as J61646-ME

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Chemical Identifiers

CAS7415-69-2

IUPAC Namedisodium hydrogen ({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)phosphonate

Molecular FormulaC10H13N5Na2O11P2

InChI KeyLTZCGDIGAHOTKN-KHRSEZDTNA-L

SMILES[Na+].[Na+].NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O)C(=O)N1

Specifications

Specification Sheet

Solution TestClear colorless solution (50 mg/ml in water)

FormPowder

Assay from Suppliers CofA≥ 96.0% (on dry basis, UV Content)

Water Content (Karl Fischer Titration)≤ 10%

Spectral RatioA250/260: 0.9 to 1.00; A280/A260: 0.63 to 0.71

Guanosine-5'-diphosphate disodium salt is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors. It is also used to study cell signaling processes mediate by guanine nucleotide exchange factors.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Guanosine-5′-diphosphate disodium salt is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors. It is also used to study cell signaling processes mediate by guanine nucleotide exchange factors.

Solubility
Soluble in water

Notes
Incompatible with strong oxidizing agents.

RUO – Research Use Only

General References:

Das, B.; Kumar, D. A.; Veena, T. Differential kinetics at PK/PEPCK branch point in the cestode, Raillietina echinobothrida. Exp. Parasitol. 2015, 153, 151-159.
Mateos-Vivas, M.; Rodríguez-Gonzalo, E.; García-Gómez, D.; Carabias-Martínez, R. Hydrophilic interaction chromatography coupled to tandem mass spectrometry in the presence of hydrophilic ion-pairing reagents for the separation of nucleosides and nucleotide mono-, di-and triphosphates. J. Chromatogr. A 2015, 1414, 129-137.