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Thermo Scientific Chemicals
4-Pentynoic acid, 95%
CAS: 6089-09-4 | C5H5O2 | 97.09 g/mol
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Chemical Identifiers
CAS6089-09-4
IUPAC Namepent-4-ynoate
Molecular FormulaC5H5O2
InChI KeyMLBYLEUJXUBIJJ-UHFFFAOYSA-M
SMILES[O-]C(=O)CCC#C
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Specifications
Specification Sheet
Specification SheetAssay (Silylated GC)≥94.0%
Appearance (Color)White to cream to yellow to pale brown
Assay (Aqueous acid-base Titration)≥94.0 to ≤106.0%
Water Content (Karl Fischer Titration)≤1.5%
FormCrystals or crystalline powder
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4-Pentynoic acid is widely utilized as a building block for the synthesis of eight sequence-defined model oligomers. Due to its triple bond at terminal carbon, it is employed as an intermediate to produce biologically active compounds. It is used as a hypoglycemic agent, which increases liver tyrosine aminotransferase and plasma corticosterone while decreasing blood sugar in rats.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
4-Pentynoic acid is widely utilized as a building block for the synthesis of eight sequence-defined model oligomers. Due to its triple bond at terminal carbon, it is employed as an intermediate to produce biologically active compounds. It is used as a hypoglycemic agent, which increases liver tyrosine aminotransferase and plasma corticosterone while decreasing blood sugar in rats.
Solubility
Soluble in low polarity organic solvents. Soluble in water.
Notes
Keep the container tightly closed in a dry and well-ventilated place. Incompatible with bases, oxidizing agents and reducing agents.
4-Pentynoic acid is widely utilized as a building block for the synthesis of eight sequence-defined model oligomers. Due to its triple bond at terminal carbon, it is employed as an intermediate to produce biologically active compounds. It is used as a hypoglycemic agent, which increases liver tyrosine aminotransferase and plasma corticosterone while decreasing blood sugar in rats.
Solubility
Soluble in low polarity organic solvents. Soluble in water.
Notes
Keep the container tightly closed in a dry and well-ventilated place. Incompatible with bases, oxidizing agents and reducing agents.
RUO – Research Use Only
General References:
- Belger, K.; Krause, N. Smaller, faster, better: modular synthesis of unsymmetrical ammonium salt-tagged NHC-gold(I) complexes and their application as recyclable catalysts in water. Org. Biomol. Chem. 2015, 13 (31), 8556-8560.
- Sahariah, P.; Sørensen, K. K.; Hjálmarsdóttir, M. A.; Sigurjónsson, O. E.; Jensen, K. J.; Másson, M.; Thygesen, M. B. Antimicrobial peptide shows enhanced activity and reduced toxicity upon grafting to chitosan polymers. Chem. Commun. 2015, 51 (58), 11611-11614.
- Hamano, H.; Nagata, K.; Fukada, N.; Shimotahira, H.; Ju, X.; Ozoe, Y. 5-[4-(3,3-Dimethylbutoxycarbonyl)phenyl]-4-pentynoic acid and its derivatives inhibit ionotropic γ-aminobutyric acid receptors by binding to the 4'-ethynyl-4-n-propylbicycloorthobenzoate site. Bioorg. Med. Chem. 2000, 8 (3), 665-674.